In breast cancer, Poly(ADP-ribose) polymerase 3 (PARP3) has been identified as a key driver of tumor aggressiveness exemplifying its selective inhibition as a promising surrogate for clinical activity onto difficult-to-treat cancers. Here we explored the
Leonel Nguekeu-Zebaze +6 more
doaj +1 more source
The NOTED software tool-set improves efficient network utilization for Rucio data transfers via FTS [PDF]
We present NOTED, a project to better exploit WAN bandwidth for Rucio and FTS data transfers. We describe the developed software tool-box and a successful demonstration of automated load-balancing in the production network.
Busse-Grawitz Coralie +5 more
doaj +1 more source
Analysis of the genes polymorphisms distribution of the MMP1, XRCC1, HFE (2), GSTT in patients with non-neoplastic melanin hyperpigmentation [PDF]
Objective: to study the factors of increased risk of hyperpigmentation, with the polymorphism of MMP1, XRCC1, HFE (2), GSTT genes and analysis of their association in patients with various clinical forms of non-neoplastic melanin hyperpigmentation ...
Ikonnikova EV +3 more
doaj
Spremljanje epidemije covid-19: Sledilnik in podatkovna infrastruktura v Sloveniji, 2021
Raziskava preučuje potek in razloge za vzpostavljanje prostovoljnega projekta COVID-19 Sledilnik, ki je nastal v času izbruha epidemije koronavirusa SARS-Cov-2 v Sloveniji in je tekom epidemije predstavljal pomemben del slovenske podatkovne ...
Kostanjevec, Jan
core +1 more source
Immunopathogenetic mechanisms of skin toxic response of antitumor therapy with mul-tikinase of angiogenesis inhibitors [PDF]
The violation of the angiogenesis is associated with pathogenesis of many diseases, but especially pronounced pathological angiogenesis underlies the growth of tumors and metastasis.
Shatokhina Е.А., Kruglova L.S.
doaj
Extracellular chloride is required for efficient platelet aggregation
Anion channels perform a diverse range of functions and have been implicated in ATP release, volume regulation, and phosphatidylserine exposure. Platelets have been shown to express several anion channels but their function is incompletely understood ...
Kirk A. Taylor +3 more
doaj +1 more source
The Suppressor of AAC2 Lethality SAL1 Modulates Sensitivity of Heterologously Expressed Artemia ADP/ATP Carrier to Bongkrekate in Yeast [PDF]
The ADP/ATP carrier protein (AAC) expressed in Artemia franciscana is refractory to bongkrekate. We generated two strains of Saccharomyces cerevisiae where AAC1 and AAC3 were inactivated and the AAC2 isoform was replaced with Artemia AAC containing a ...
Adam-Vizi, Vera +48 more
core +1 more source
Raziskava Novanormalnost, 2020
Z raziskavo Novanormalnost se je spremljalo odziv slovenske javnosti na nove razmere nastale zaradi razglasitve pandemije novega koronavirusa COVID-19. Raziskava je vsebovala ključne indikatorje odzivanja javnosti na ukrepe in doživljanje vsakodnevnega ...
Hohkraut, Tomaž +3 more
core +2 more sources
Regulation of metabolic pathways PVY-RNA biosynthesis in tobacco: glycolytic pathway
Tobacco plants infected with potato virus Y were studied at the stage of acute infection. Key enzymes of the glycolytic pathway, their regulation and the content of involved intermediates were monitored.
Luděk Šindelář +1 more
doaj +1 more source
Study of the Potential of Water Treatment Sludges in the Removal of Emerging Pollutants
Presently, water quantity and quality problems persist both in developed and developing countries, and concerns have been raised about the presence of emerging pollutants (EPs) in water.
Rita Dias +10 more
doaj +1 more source

