Results 31 to 40 of about 281,775 (299)

Molecular Characterization of a Novel Intracellular ADP-Ribosyl Cyclase

, 2007
Background. ADP-ribosyl cyclases are remarkable enzymes capable of catalyzing multiple reactions including the synthesis of the novel and potent intracellular calcium mobilizing messengers, cyclic ADP-ribose and NAADP.
Jonathan S Marchant, Marchant, JS, Michael J Boulware, Dev Churamani, Churamani, D, Dale, L, Geach Timothy J., Martin Andrew C.R., Gary W Moy, Andrew C R Martin, Sandip Patel, Dale Leslie, Yi-Hsien Su, Vacquier, VD, Vacquier Victor D., Su, YH, Patel Sandip, Churamani Dev, Boulware, MJ, Marchant Jonathan S., Leslie Dale, Boulware Michael J., Moy Gary W., Patel, S, Geach, TJ, Su Yi-Hsien, Moy, GW, Timothy J Geach, Martin, ACR, Victor D Vacquier   +29 more
core   +1 more source

ADP-dependent Phosphofructokinases in Mesophilic and Thermophilic Methanogenic Archaea

, 2001
Phosphofructokinase (PFK) is a key enzyme of the glycolytic pathway in all domains of life. Two related PFKs, ATP-dependent and PPi-dependent PFK, have been distinguished in bacteria and eucarya, as well as in some archaea.
Kengen, S.W.M., Vos, W.M., de, Verhees, C.H., Tuininga, J.E., van der Oost, J., Stams, A.J.M., Oost, J., van der, de Vos, W.M.   +7 more
core   +1 more source

The crystal structure of the Y140F mutant of ADP-L-glycero-D-manno-heptose 6-epimerase bound to ADP-beta-D-mannose suggests a one base mechanism

, 2010
Supported by Wellcome Trust grant 081862/Z/06/ZBacteria synthesize a wide array of unusual carbohydrate molecules, which they use in a variety of ways.
Naismith, Jim, Kowatz, Thomas, Tanner, Martin E., Morrison, James P.   +3 more
core   +1 more source

MARTs and MARylation in the Cytosol: Biological Functions, Mechanisms of Action, and Therapeutic Potential

Cells, 2021
Mono(ADP-ribosyl)ation (MARylation) is a regulatory post-translational modification of proteins that controls their functions through a variety of mechanisms. MARylation is catalyzed by mono(ADP-ribosyl) transferase (MART) enzymes, a subclass of the poly(
Sridevi Challa, MiKayla S. Stokes, W. Lee Kraus   +2 more
doaj   +1 more source

Sledenje priporočilom za omejitev epidemije, 2020

, 2020
Neodvisni strokovnjaki z različnih področij povezani kot člani civilnih iniciativ Sledilnik COVID-19 in Mladi zdravniki so sredi novembra 2020 izvedli anketo, s katero so želeli ugotoviti, v kolikšni meri so prebivalci Slovenije sledili priporočilom za ...
Muršič, Zarja, Luštrik, Roman, Zorko, Andraž, Zupanič, Sanja, Slavec, Ana   +4 more
core   +2 more sources

Potentiation of TRAP-6-induced platelet dense granule release by blockade of P2Y12 signaling with MRS2395

Platelets, 2018
The release of ADP from platelet dense granules and its binding to platelet P2Y12 receptors is key to amplifying the initial hemostatic response and propagating thrombus formation.
Annachiara Mitrugno, Rachel A. Rigg, Nicole B. Laschober, Anh T. P. Ngo, Jiaqing Pang, Craig D. Williams, Joseph E. Aslan, Owen J. T. McCarty   +7 more
doaj   +1 more source

Anti-platelet therapy: ADP receptor antagonists.

, 2011
The P2Y(12) receptor on platelets with which ADP interacts has an important role in promoting platelet function and thereby platelet involvement in both haemostasis and thrombosis.
Heptinstall, S, Wijeyeratne, YD, Stan Heptinstall, Yanushi Dullewe Wijeyeratne   +3 more
core   +1 more source

MiCREATE - Priseljeni otroci in priseljenske skupnosti v spreminjajoči se Evropi, 2019

, 2019
Projekt MiCreate (Migrant Children and Communities in a Transforming Europe) je mednarodni projekt, v okviru katerega je bila opravljena primerjalna raziskava v šolah, kjer so poleg Slovenije (koordinator projekta) sodelovale tudi Avstrija, Danska ...
Medarić, Zorana, Gornik, Barbara, Dežan, Lucija, Zadel, Maja, Sedmak, Mateja   +4 more
core   +2 more sources

Characterization of an Aedes ADP-Ribosylation Protein Domain and Role of Post-Translational Modification during Chikungunya Virus Infection

Pathogens, 2023
Poly ADP-ribose polymerases (PARPs) catalyze ADP-ribosylation, a subclass of post-translational modification (PTM). Mono-ADP-ribose (MAR) moieties bind to target molecules such as proteins and nucleic acids, and are added as part of the process which ...
Ramesh Kumar, Divya Mehta, Debasis Nayak, Sujatha Sunil   +3 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source