Results 41 to 50 of about 281,775 (299)
Platelets, 2018 On activation platelets release microRNAs and extracellular vesicles (EV) into circulation. The release of EV from platelets has been shown to be dependent on the agonist; in this study, we investigated whether the microRNA profile or EV released from ...
Ashley R. Ambrose +3 more
doaj +1 more source
Fehérje ADP-riboziláció tanulmányozása egy ADP-ribóz kötő fehérjedomén segítségével
, 2021 A több mint 20 ismert ADP-riboziltranszferáz (ART) által létrehozott fehérjemódosítások nagy része a szabályozott folyamatokkal együtt még felderítésre vár. Különösen igaz ez a mono(ADP-ribóz) (MAR) fehérjemódosításokra.
Kiss, Fanni
core
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Perbedaan Pengaruh Pemberian Etomidate Dan Penthotal Terhadap Agregasi Trombosit
JAI (Jurnal Anestesiologi Indonesia), 2011 Latar Belakang: Perdarahan perioperatif sering dijumpai dalam setiap operasi. Penggunaan obat anestesi induksi (etomidat dan pentotal) berpengaruh dalam menghambat agregasi trombosit.
Noor Hadi +2 more
doaj +1 more source
ADP-ribosylation: from molecular mechanisms to human disease
, 2020 Post-translational modification of proteins by ADP-ribosylation, catalysed by poly (ADP-ribose) polymerases (PARPs) using NAD+ as a substrate, plays central roles in DNA damage signalling and repair, modulates a range of cellular signalling cascades and ...
Nicolas C. Hoch (8141358) +1 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Perbedaan Pengaruh Pemberian Enfluran dan Halotan Terhadap Agregasi Trombosit
JAI (Jurnal Anestesiologi Indonesia), 2010 Latar belakang: Perdarahan perioperatif merupakan masalah serius yang sering dihadapi dalam setiap operasi. Penggunaan obat anestesi inhalasi dikatakan mempunyai pengatuh dalam menghambat agregasi trombosit.
Agatha Citrawati Anom +1 more
doaj +1 more source
ADP-Ribosylation in Antiviral Innate Immune Response
Pathogens, 2023 Adenosine diphosphate (ADP)-ribosylation is a reversible post-translational modification catalyzed by ADP-ribosyltransferases (ARTs). ARTs transfer one or more ADP-ribose from nicotinamide adenine dinucleotide (NAD+) to the target substrate and release ...
Qian Du, Ying Miao, Wei He, Hui Zheng
doaj +1 more source
ADP-ribosylation of DNA and RNA
DNA Repair, 2021 ADP-ribosylation is a chemical modification of macromolecules found across all domains of life and known to regulate a variety of cellular processes. Notably, it has a well-established role in the DNA damage response. While it was historically known as a post-translational modification of proteins, recent studies have shown that nucleic acids can also ...
Groslambert, Joséphine +2 more
openaire +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source