Results 71 to 80 of about 14,953 (260)
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Robust Approximate Optimal Trajectory Tracking Control for Quadrotors
AerospaceThis paper uses the adaptive dynamic programming (ADP) method to achieve optimal trajectory tracking control for quadrotors. Relying on an established mathematical model of a quadrotor, the approximate optimal trajectory tracking control, which consists ...
Rong Li +5 more
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Dynamic Programming with Approximation Function for Nurse Scheduling [PDF]
, 2016 Although dynamic programming could ideally solve any combinatorial optimization problem, the curse of dimensionality of the search space seriously limits its application to large optimization problems. For example, only few papers in the literature have reported the application of dynamic programming to workforce scheduling problems.
Peng Shi 0017, Dario Landa-Silva
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FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Expected Duration of Dynamic Markov PERT Networks
International Journal of Industrial Engineering and Production Research, 2007 : In this paper , we apply the stochastic dynamic programming to approximate the mean project completion time in dynamic Markov PERT networks. It is assumed that the activity durations are independent random variables with exponential distributions, but ...
A. Azaron, S.M. Fatemi Ghomi
doaj
Pareto Optimal Solutions for Stochastic Dynamic Programming Problems via Monte Carlo Simulation
Journal of Applied Mathematics, 2013 A heuristic algorithm is proposed for a class of stochastic discrete-time continuous-variable dynamic programming problems submitted to non-Gaussian disturbances.
R. T. N. Cardoso +2 more
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Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Adaptive Modulation with Smoothed Flow Utility
EURASIP Journal on Wireless Communications and Networking, 2010 We consider the problem of choosing the data flow rate on a wireless link with randomly varying channel gain, to optimally trade off average transmit power and the average utility of the smoothed data flow rate.
Akuiyibo Ekine, Boyd Stephen
doaj
Stable Function Approximation in Dynamic Programming [PDF]
, 1995 The success of reinforcement learning in practical problems depends on the ability to combine function approximation with temporal difference methods such as value iteration. Experiments in this area have produced mixed results; there have been both notable successes and notable disappointments.
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