Results 111 to 120 of about 394,451 (234)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

On the functional independence of numerical acuity and visual working memory

Frontiers in Psychology
Deciding where to direct our vehicle in a crowded parking area or where to line up at an airport gateway relies on our ability to appraise the numerosity of multitudes at a glimpse and react accordingly.
Roberto Dell’Acqua, Roberto Dell’Acqua, Paola Sessa, Paola Sessa, Sabrina Brigadoi, Judit Gervain, Judit Gervain, Roy Luria, Roy Luria, Mattia Doro   +9 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

The human visual system spontaneously computes approximate number.

, 2021
Is numerosity an abstraction that arises downstream of basic perceptual processing, or does the brain process numerosity like a primary perceptual feature such as color or motion? Here, we tested whether visual cortex computes number automatically, even when number is task-irrelevant and is being processed unconsciously.
Lucero, Che, Quirk, Colin T, Goldin-Meadow, Susan, Vogel, Edward, Casasanto, Daniel   +4 more
openaire   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Associations among socioeconomic status and preschool-aged children's, number skills, and spatial skills: The role of executive function. [PDF]

J Exp Child Psychol, 2022
Bachman HJ, Miller P, Elliott L, Duong S, Libertus M, Votruba-Drzal E.   +5 more
europepmc   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

FEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino, Giuliana Fusco, Alfonso De Simone   +2 more
wiley   +1 more source

Same digits, different magnitudes: manual reaching unveils dual systems in symbolic number representation

BMC Psychology
The role of Approximate Number System (ANS) in adult symbolic number processing remains controversial. Despite evidences for a linear and precise representation of symbolic numbers in adults, this study, based on Dual-Process Theory (DPT), proposes that ...
Danni Liang, Yuanyuan Wang, Zhongting Chen, Ciping Deng   +3 more
doaj   +1 more source

Effect of approximate system training on mathematical ability

Cogent Psychology
An approximate number system (ANS) enables individuals to estimate and mentally manipulate quantities without using any form of numerical symbols. Controlling the balance of gender ratio, 51 college students aged 19–24 years were randomly assigned to ...
Jian Zhu, Qing Liu, Wenjuan Zhang
doaj   +1 more source