Results 111 to 120 of about 1,947,664 (252)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Large-scale study of the precision of the approximate number system: Differences between formats, heterogeneity and congruency effects. [PDF]

Heliyon, 2023
Malykh S, Tarasov S, Baeva I, Nikulchev E, Kolyasnikov P, Ilin D, Marnevskaia I, Malykh A, Ismatullina V, Kuzmina Y.   +9 more
europepmc   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Estimating on the fly: The approximate number system in rufous hummingbirds (Selasphorus rufus). [PDF]

Learn Behav, 2021
Corliss M, Brown T, Hurly TA, Healy SD, Tello-Ramos MC.   +4 more
europepmc   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Estimation of Importance: Relative Contributions of Symbolic and Non-Symbolic Number Systems to Exact and Approximate Calculation

Journal of Numerical Cognition, 2017
The topic of how symbolic and non-symbolic number systems relate to exact calculation skill has received great discussion for a number of years now. However, little research has been done to examine how these systems relate to approximate calculation ...
Rylan J. Waring, Marcie Penner-Wilger
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Attentional bias induced by stimulus control (ABC) impairs measures of the approximate number system. [PDF]

Atten Percept Psychophys, 2021
Lindskog M, Poom L, Winman A.
europepmc   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Developmental changes in numerosity and area perception in school-age children

Acta Psychologica
Humans can quickly estimate the quantity of objects in their environment through the Approximate Number System (ANS). However, the developmental trajectories of numerical and spatial perception in school-aged children are not well understood.
Linlin Yan, Ping Qian, Ruoyuan Yan
doaj   +1 more source