Results 131 to 140 of about 1,947,664 (252)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

On the functional independence of numerical acuity and visual working memory

Frontiers in Psychology
Deciding where to direct our vehicle in a crowded parking area or where to line up at an airport gateway relies on our ability to appraise the numerosity of multitudes at a glimpse and react accordingly.
Roberto Dell’Acqua, Roberto Dell’Acqua, Paola Sessa, Paola Sessa, Sabrina Brigadoi, Judit Gervain, Judit Gervain, Roy Luria, Roy Luria, Mattia Doro   +9 more
doaj   +1 more source

Associations among socioeconomic status and preschool-aged children's, number skills, and spatial skills: The role of executive function. [PDF]

J Exp Child Psychol, 2022
Bachman HJ, Miller P, Elliott L, Duong S, Libertus M, Votruba-Drzal E.   +5 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

The human visual system spontaneously computes approximate number

, 2021
Is numerosity an abstraction that arises downstream of basic perceptual processing, or does the brain process numerosity like a primary perceptual feature such as color or motion? Here, we tested whether visual cortex computes number automatically, even when number is task-irrelevant and is being processed unconsciously.
Lucero, Che, Quirk, Colin T, Goldin-Meadow, Susan, Vogel, Edward, Casasanto, Daniel   +4 more
openaire   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Active information seeking using the Approximate Number System [PDF]

, 2019
Human adults share the ability to approximate large quantitieswithout counting with newborn infants and non-human species.This ability is supported by the Approximate Number System(ANS) - a primitive and domain-specific cognitive system thatsupports noisy numerical decisions. How does the ANS supportactive exploratory decisions?
Wang, Jinjing, Bonawitz, Elizabeth
openaire  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Same digits, different magnitudes: manual reaching unveils dual systems in symbolic number representation

BMC Psychology
The role of Approximate Number System (ANS) in adult symbolic number processing remains controversial. Despite evidences for a linear and precise representation of symbolic numbers in adults, this study, based on Dual-Process Theory (DPT), proposes that ...
Danni Liang, Yuanyuan Wang, Zhongting Chen, Ciping Deng   +3 more
doaj   +1 more source

Effect of approximate system training on mathematical ability

Cogent Psychology
An approximate number system (ANS) enables individuals to estimate and mentally manipulate quantities without using any form of numerical symbols. Controlling the balance of gender ratio, 51 college students aged 19–24 years were randomly assigned to ...
Jian Zhu, Qing Liu, Wenjuan Zhang
doaj   +1 more source