Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
The Approximate Number System and Mathematical Abilities in Chinese Preschoolers With and Without Autism Spectrum Disorder. [PDF]
Chen L, Zhong Z, Jiang W.
europepmc +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
APPROXIMATE CORES OF GAMES AND ECONOMIES WITH CLUBS [PDF]
We introduce the framework of parameterized collections of games with and without side payments and provide three no emptiness of approximate core theorems for games in parameterized collections.
Wooders, Myrna Holtz +1 more
core
Effects of non-symbolic arithmetic training on symbolic arithmetic and the approximate number system. [PDF]
Au J, Jaeggi SM, Buschkuehl M.
europepmc +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Chebyshev polynomial approximation to approximate partial differential equations [PDF]
This pa per suggests a simple method based on Chebyshev approximation at Chebyshev nodes to approximate partial differential equations. The methodology simply consists in determining the value function by using a set of nodes and basis functions.
Guglielmo Maria Caporale, Mario Cerrato
core
Differential contributions of approximate number system, number line estimation, and working memory to mathematical skills in preschool and primary school. [PDF]
Hischa V +3 more
europepmc +1 more source
Fluency in symbolic arithmetic refines the approximate number system in parietal cortex. [PDF]
Suárez-Pellicioni M, Booth JR.
europepmc +1 more source
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source

