Results 131 to 140 of about 178,942 (307)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Convergence of approximate solutions of variational problems

open access: yes, 2009
We study the structure of approximate solutions of autonomous variational problems on large finite intervals. In our previous research, which was summarized in Zaslavski (2006b), we showed that approximate solutions are determined mainly by the integrand,
Zaslavski, A. J.
core  

A note on rapid convergence of approximate solutions for second order periodic boundary value problems [PDF]

open access: yes, 2005
summary:In this paper, we develop a generalized quasilinearization technique for a nonlinear second order periodic boundary value problem and obtain a sequence of approximate solutions converging uniformly and quadratically to a solution of the problem ...
Khan, Rahmat A., Ahmad, Bashir
core  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Legendre Operational Differential Matrix for Solving Fuzzy Differential Equations with Trapezoidal Fuzzy Function Coefficients

open access: yesJournal of Kufa for Mathematics and Computer
In this work, we used the Legendre operational differential matrix method based on Tau method to obtain the fuzzy approximate-analytical solutions of the fuzzy differential equations in which the coefficients are trapezoidal fuzzy function.
zainab imran, Mazin H. Suhhiem
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Chebyshev polynomial approximation to approximate partial differential equations [PDF]

open access: yes
This pa per suggests a simple method based on Chebyshev approximation at Chebyshev nodes to approximate partial differential equations. The methodology simply consists in determining the value function by using a set of nodes and basis functions.
Guglielmo Maria Caporale, Mario Cerrato
core  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Tools for the Verification of Approximate

open access: yes, 2007
Scientific computation is often carried out in general purpose problem solving environments (PSEs) such as MATLAB or MAPLE or in application-specific PSEs such as those associated with large scale, high performance simulations. When practitioners work
Solutions To Differential, W. H. Enright
core  

Home - About - Disclaimer - Privacy