Results 181 to 190 of about 3,086,260 (319)
Tackling High Dimensionality in QSP: Guiding Model Order Reduction With Index Analysis. [PDF]
CPT Pharmacometrics Syst PharmacolTillil J, Huisinga W, Knöchel J.
europepmc +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Exciton-Defect Interaction and Optical Properties from a First-Principles T-Matrix Approach. [PDF]
Nano LettChan YH +4 more
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
A Wasserstein-Space-Based Framework for Processing Fiber Orientation Geometry in Diffusion MRI. [PDF]
IEEE Trans Med ImagingNie X, Shi Y.
europepmc +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Improved Semiclassical Quantization of Bound States. [PDF]
J Phys Chem LettPollak E.
europepmc +1 more source
Approximations and inequalities for the exponential beta function [PDF]
, 2019 Sever S Dragomir, Farzad Khosrowshahi
openalex +1 more source