Results 111 to 120 of about 129,306 (313)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Approximation hardness of dominating set problems in bounded degree graphs

open access: yes, 2008
We study approximation hardness of the Minimum Dominating Set problem and its variants in undirected and directed graphs. Using a similar result obtained by Trevisan for Minimum Set Cover we prove the first explicit approximation lower bounds for various
Chlebikova, Janka   +4 more
core   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Approximation Algorithms for Noncommutative CSPs [PDF]

open access: yes2024 IEEE 65th Annual Symposium on Foundations of Computer Science (FOCS)
74 pages, 8 figures, revisions targeting only the clarity of the ...
Culf, Eric   +2 more
openaire   +2 more sources

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Recommending Links to Control Elections via Social Influence

open access: yesAlgorithms, 2019
Political parties recently learned that they must use social media campaigns along with advertising on traditional media to defeat their opponents.
Federico Corò   +2 more
doaj   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Local RBF approximation for scattered data fitting with bivariate splines [PDF]

open access: yes, 2005
In this paper we continue our earlier research [4] aimed at developing effcient methods of local approximation suitable for the first stage of a spline based two-stage scattered data fitting algorithm.
Oleg Davydov   +5 more
core   +1 more source

Special Issue on “Algorithm Engineering: Towards Practically Efficient Solutions to Combinatorial Problems”

open access: yesAlgorithms, 2019
The purpose of this special issue of Algorithms was to attract papers presenting original research in the area of algorithm engineering. In particular, submissions concerning the design, analysis, implementation, tuning, and experimental evaluation of ...
Mattia D’Emidio, Daniele Frigioni
doaj   +1 more source

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