Results 81 to 90 of about 223,993 (286)

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Floor, ceiling and the space between

Annals of the West University of Timisoara: Mathematics and Computer Science
Motivated by a question on the ranges of the commutators of dilated floor functions in [10], together with a related problem in [3], we investigate the precise ranges of certain generalized polynomials dependent on a real parameter. Our analysis requires
Bényi Árpád, Ćurgus Branko
doaj   +1 more source

Rational choice by two sequential criteria [PDF]

This paper contributes to the theory of rational choice under multiple criteria. We perform a preliminary study of the properties of decision made by the sequential application of rational choices.
Alcantud, José Carlos R., García-Sanz, María D.   +1 more
core   +1 more source

Central limit theorems in the geometry of numbers

, 2017
We investigate in this paper the distribution of the discrepancy of various lattice counting functions. In particular, we prove that the number of lattice points contained in certain domains defined by products of linear forms satisfies a Central Limit ...
Björklund, Michael, Gorodnik, Alexander
core   +1 more source

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang, Brian S. Gloss, Jessica P. Hayes, Andrew J. A. Holland, Manoj P. Menezes, Joceline A. Branson, Shekeeb S. Mohammad, Jingya J. Yan, Shrujna Patel, Velda X. Han, Russell C. Dale   +10 more
wiley   +1 more source

Approximate truncated balanced realizations for infinite dimensional systems [PDF]

This paper presents an approximate method for obtaining truncated balance realizations of systems represented by non-rational transfer functions, that is infinite dimensional systems.
Deabreu-Garcia, J. Alex, Hartley, Tom T.
core   +1 more source

Non-archimedean Yomdin-Gromov parametrizations and points of bounded height

, 2015
We prove an analogue of the Yomdin-Gromov Lemma for $p$-adic definable sets and more broadly in a non-archimedean, definable context. This analogue keeps track of piecewise approximation by Taylor polynomials, a nontrivial aspect in the totally ...
Cluckers, R., Comte, G., Loeser, F.
core   +1 more source

Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz, Neha V. Safi, Iliana Pliska‐Bloch, Ulrike W. Kaunzner, Ha Luu, Yi Wang, Thanh D. Nguyen, Sandra Hurtado Rúa, Susan A. Gauthier   +8 more
wiley   +1 more source

About the rate of rational approximation of some analytic functions

Mathematical Modelling and Analysis, 1998
The article is devoted to results relating to the theory of rational approximation of an analytic function. Let ƒ be an analytic function on the disk {z : |z| < ñ), ñ > 1. The rate of decrease of the best approximations ñn of a function ƒ by the rational
A. YA. Radyno
doaj   +1 more source

Rational approximations in Analytic QCD

, 2009
We consider the ``modified Minimal Analytic'' (mMA) coupling that involves an infrared cut to the standard MA coupling. The mMA coupling is a Stieltjes function and, as a consequence, the paradiagonal Pade approximants converge to the coupling in the ...
Baker G A, Cvetič G Martínez H E, Davier M Höcker A Zhang Z, Gardi E, Gorazd Cvetič, Héctor E Martínez, Shirkov D V Solovtsov I L   +6 more
core   +1 more source