Results 151 to 160 of about 148,991,006 (286)

Ray Marching Aspheric Surfaces: Robust Ray Intersection Calculation for Design of Optical Sensors. [PDF]

Sensors (Basel)
Sanzharov V, Ershov S, Frolov V, Galaktionov V, Voloboy A.   +4 more
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

High-Frequency Dynamics and Electrical Signatures of a 3D Bloch Point. [PDF]

Nanomaterials (Basel)
Gareeva Z, Gareev S, Filippova V, Sharafullin I.   +3 more
europepmc   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Inverse scattering in biological samples via beam propagation. [PDF]

Sci Adv
Kim J, Bolton B, Moshksayan K, Khanna R, Swartz ME, Ziemczonok M, Kamra M, Allenspach K, Parekh SH, Kujawińska M, Eberhart JK, Sarinay Cenik E, Ben-Yakar A, Chowdhury S.   +13 more
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Optical diffraction tomographic microscopy: a cutting-edge label-free three-dimensional bioimaging. [PDF]

Biophys Rep
Min J, Gao P, Yuan X, Xue Y, Liu R, Feng Y, Wang S, Li Y, Wen K, Yang L, Wu T, Yao B.   +11 more
europepmc   +1 more source

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

FEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn, Artur Osyczka, Marcin Sarewicz   +2 more
wiley   +1 more source

Rectus Abdominis Sheath Inversion Flap Reinforced With Polypropylene Mesh (RASIFRPM): A Reconstructive Alternative for the Management of Complex Ventral Hernia. [PDF]

Cureus
Maldonado Barrios IL, Barahona Browne FJ, Cervantes Ruiz LA, Ramirez Aguilar JA, Smolinski Kurek RL.   +4 more
europepmc   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source