Results 131 to 140 of about 54,457 (295)

Approximation by complex Bernstein-Stancu polynomials in compact disks [PDF]

open access: yes, 2013
Bu çalışmada öncelikle reel değişkenli Bernstein, Bernstein-Stancu ve Kantorovich-Stancu polinomlarının yaklaşım özellikleri incelendi. İkinci olarak analitik fonksiyonlara ilişkin kompleks Bernstein, kompleks Bernstein-Stancu ve Kantorovich-Stancu ...
Altınok, Maya
core  

Greedy Thiele continued-fraction approximation on continuum domains in the complex plane

open access: yesCoRR
We describe an adaptive greedy algorithm for Thiele continued-fraction approximation of a function defined on a continuum domain in the complex plane. The algorithm iteratively selects interpolation nodes from an adaptively refined set of sample points on the domain boundary.
Tobin A. Driscoll, Yuxing Zhou
openaire   +2 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Stability and covergence properties of Bergman Kernel methods for numerical conformal mapping [PDF]

open access: yes, 1984
In this paper we study the stability and convergence properties of Bergman kernel methods, for the numerical conform al mapping of simply and doubly- connected domains.
Warby, M K, Papamichael, N
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Approximate Solutions of the Fisher–Kolmogorov Equation in an Analytic Domain of the Complex Plane

open access: yesSymmetry
The paper oresents the analytical construction of approximate solutions to the generalized Fisher–Kolmogorov equation in the complex domain. The existence and uniqueness of such solutions are established within an analytic domanin of the complex plane.
Victor Orlov, Alexander V. Chichurin
openaire   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

open access: yesFEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring   +3 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

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