Results 81 to 90 of about 148,991,006 (286)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Rational approximation of arbitrary order operators-Strange scaling equations

四川大学学报. 自然科学版, 2020
Two new types of irregular scaling equations-strange scaling equations are obtained by the continuous expansion method and scale expansion theory. This paper explores the differences and advantages of the rational function sequences of strange scaling ...
GUO ZhaoRu, HE QiuYan, YUAN Xiao, PU YiFei   +3 more
doaj  

Evanescent waves and deaf bands in sonic crystals

AIP Advances, 2011
The properties of sonic crystals (SC) are theoretically investigated in this work by solving the inverse problem k(ω) using the extended plane wave expansion (EPWE).
V. Romero-García, L. M. Garcia-Raffi, J. V. Sánchez-Pérez   +2 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

NAVIER–STOKES EQUATIONS ON THE β-PLANE [PDF]

, 2012
Mathematical analysis has been undertaken for the vorticity formulation of the two dimensional Navier–Stokes equation on the β-plane with periodic boundary conditions. This equation describes the flow of fluid near the equator of the Earth. The long time
Al-Jaboori, Mustafa Ali Hussain, AL-JABOORI, MUSTAFA,ALI,HUSSAIN   +1 more
core  

On the complex least squares problem with constrained phase [PDF]

, 2011
The problem of solving approximately in the least squares sense an overdetermined linear system of equations with complex valued coefficients is considered, where the elements of the solution vector are constrained to have the same phase.
Markovsky, Ivan
core   +2 more sources

Integral characteristics and distribution of roots of entire functions

Вестник Самарского университета: Естественнонаучная серия
We establish new relationships between the distribution of roots of entire functions and certain integral characteristics of the logarithms of the modules of these entire functions. These integral characteristics are constructed on the basis of arbitrary
E. B. Menshikova, B. N. Khabibullin
doaj   +1 more source

Electronic Structure of 1,3-dicarbomethoxy4,6-benzenedicarboxylic acid: Density Functional Approach

International Journal of Electrochemical Science, 2013
Structural optimization of 1,3-dicarbomethoxy4,6-benzenedicarboxylic acid single crystal was performed by minimizing the forces which act on the atoms. The optimized geometry was used to perform the theoretical study of electronic properties, electronic ...
Sikander Azam, A.H. Reshak
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source