Results 51 to 60 of about 277,649 (266)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
On the Approximability of Digraph Ordering [PDF]
Algorithmica, 2015 Given an n-vertex digraph D = (V, A) the Max-k-Ordering problem is to compute a labeling $\ell : V \to [k]$ maximizing the number of forward edges, i.e. edges (u,v) such that $\ell$(u) < $\ell$(v). For different values of k, this reduces to Maximum Acyclic Subgraph (k=n), and Max-Dicut (k=2).
Kenkre, Sreyash +3 more
openaire +2 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Approximation of Second-Order Moment Processes from Local Averages
Journal of Inequalities and Applications, 2009 We use local averages to approximate processes that have finite second-order moments and are continuous in quadratic mean. We also provide some insight and generalization of the connection between Bernstein polynomials and Brownian motion, which was ...
Song Zhanjie, Wang Ping, Xie Weisong
doaj +2 more sources
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
High-Order Steady-State Diffusion Approximations
Operations ResearchMuch like higher-order Taylor expansions allow one to approximate functions to a higher degree of accuracy, we demonstrate that, by accounting for higher-order terms in the Taylor expansion of a Markov process generator, one can derive novel diffusion approximations that achieve a higher degree of accuracy compared with the classical ones used in the ...
Anton Braverman, J. G. Dai, Xiao Fang
openaire +3 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Abel–Goncharov Type Multiquadric Quasi-Interpolation Operators with Higher Approximation Order
Journal of Mathematics, 2021 A kind of Abel–Goncharov type operators is surveyed. The presented method is studied by combining the known multiquadric quasi-interpolant with univariate Abel–Goncharov interpolation polynomials.
Ruifeng Wu
doaj +1 more source