Results 61 to 70 of about 9,849,612 (295)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Contextual Approximation and Higher-Order Procedures [PDF]

open access: yes, 2016
We investigate the complexity of deciding contextual approximation (refinement) in finitary Idealized Algol, a prototypical language combining higher-order types with state. Earlier work in the area established the borderline between decidable and undecidable cases, and focussed on the complexity of deciding approximation between terms in normal form ...
Ranko Lazic 0001, Andrzej S. Murawski
openaire   +2 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Approximation Order for Multivariate Durrmeyer Operators with Jacobi Weights

open access: yesAbstract and Applied Analysis, 2011
Using the equivalence relation between K-functional and modulus of smoothness, we establish a strong direct theorem and an inverse theorem of weak type for multivariate Bernstein-Durrmeyer operators with Jacobi weights on a simplex in this paper. We also
Jianjun Wang, Chan-Yun Yang, Shukai Duan
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Numerical approximation of Newell-Whitehead-Segel equation of fractional order

open access: yesNonlinear Engineering, 2016
The aim of the present work is to propose a user friendly approach based on homotopy analysis method combined with Sumudu transform method to drive analytical and numerical solutions of the fractional Newell-Whitehead-Segel amplitude equation which ...
Kumar Devendra, Sharma Ram Prakash
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Linear stationary iterative methods for the force-based quasicontinuum approximation [PDF]

open access: yes, 2012
Force-based multiphysics coupling methods have become popular since they provide a simple and efficient coupling mechanism, avoiding the difficulties in formulating and implementing a consistent coupling energy.
Luskin, Mitchell Barry   +1 more
core   +1 more source

Approximation of Second-Order Moment Processes from Local Averages

open access: yesJournal of Inequalities and Applications, 2009
We use local averages to approximate processes that have finite second-order moments and are continuous in quadratic mean. We also provide some insight and generalization of the connection between Bernstein polynomials and Brownian motion, which was ...
Zhanjie Song, Ping Wang, Weisong Xie
doaj   +2 more sources

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