Results 81 to 90 of about 286,746 (266)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The Second-Order Born Approximation in Diffuse Optical Tomography
Journal of Applied Mathematics, 2012 Diffuse optical tomography is used to find the optical parameters of a turbid medium with infrared red light. The problem is mathematically formulated as a nonlinear problem to find the solution for the diffusion operator mapping the optical coefficients
Kiwoon Kwon
doaj +1 more source
Approximation method for a fractional order transfer function with zero and pole
Archives of Control Sciences, 2014 The paper presents an approximation method for elementary fractional order transfer function containing both pole and zero. This class of transfer functions can be applied for example to build model - based special control algorithms. The proposed method
Oprzędkiewicz Krzysztof
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Improved first order mean spherical approximation for simple fluids
Condensed Matter Physics, 2011 A perturbation approach based on the first-order mean spherical approximation (FMSA) is proposed. It consists in adopting a hard-sphere plus short-range attractive Yukawa fluid as the novel reference system, over which the perturbative solution of the ...
I. Nezbeda, A. Trokhymchuk, S. Hlushak
doaj +1 more source
The cubic non-linearity of order ε in the second approximation
Vietnam Journal of Mechanics, 1999 None
Nguyen Van Dinh
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
High order approximation theory for Banach space valued functions
Journal of Numerical Analysis and Approximation Theory, 2017 Here we study quantitatively the high degree of approximation of sequences of linear operators acting on Banach space valued di§erentiable functions to the unit operator. These operators are bounded by real positive linear companion operators.
George A. Anastassiou
doaj +2 more sources