Results 71 to 80 of about 369,812 (312)
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Justification of the Cauchy-Born approximation of elastodynamics [PDF]
, 2013 We present sharp convergence results for the Cauchy-Born approximation of general classical atomistic interactions, for static problems with small data and for dynamic problems on a macroscopic time ...
Ortner, Christoph, Theil, Florian
core +1 more source
Approximation of Second-Order Moment Processes from Local Averages
Journal of Inequalities and Applications, 2009 We use local averages to approximate processes that have finite second-order moments and are continuous in quadratic mean. We also provide some insight and generalization of the connection between Bernstein polynomials and Brownian motion, which was ...
Zhanjie Song, Ping Wang, Weisong Xie
doaj +2 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Optimal order for approximation of derivatives
Journal of Computer and System Sciences, 1979 AbstractIn this note, we show that the central difference formula for approximating f′(0) using the information {f(jh): −r ⩽j ⩽r} has maximal order of accuracy among all algorithms using this information. The technique used is an adaptation of the order-of-information approach of Wozniakowski.
openaire +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
A logarithmic approximation of linearly ordered colourings
CoRRA linearly ordered (LO) $k$-colouring of a hypergraph assigns to each vertex a colour from the set $\{0,1,\ldots,k-1\}$ in such a way that each hyperedge has a unique maximum element. Barto, Batistelli, and Berg conjectured that it is NP-hard to find an LO $k$-colouring of an LO 2-colourable 3-uniform hypergraph for any constant $k\geq 2$ [STACS'21 ...
Håstad, J +3 more
openaire +6 more sources
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Rational approximation of arbitrary order operators-Strange scaling equations
四川大学学报. 自然科学版, 2020 Two new types of irregular scaling equations-strange scaling equations are obtained by the continuous expansion method and scale expansion theory. This paper explores the differences and advantages of the rational function sequences of strange scaling ...
GUO ZhaoRu +3 more
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