Results 91 to 100 of about 369,812 (312)

Error estimation of a proper orthogonal decomposition reduced model of a permanent magnet synchronous machine [PDF]

, 2014
Model order reduction methods, like the proper orthogonal decomposition (POD), enable to reduce dramatically the size of a finite element (FE) model.
MAC, Hung, CLENET, Stephane, HENNERON, Thomas   +2 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Multiresolution Expansion and Approximation Order of Generalized Tempered Distributions

International Journal of Mathematics and Mathematical Sciences, 2013
Let be the generalized tempered distributions of -growth with restricted order , where the function grows faster than any linear functions as . We show the convergence of multiresolution expansions of in the test function space of .
Byung Keun Sohn
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

An Improved Approximation to the Distributions in GMM Estimation [PDF]

The empirical saddlepoint distribution provides an approximation to the sampling distributions for the GMM parameter estimates and the statistics that test the overidentifying restrictions.
Fallaw Sowell
core  

The evaluation of the order of approximation of the matrix method for numerical integration of the boundary value problems for systems of linear non-homogeneous ordinary differential equations of the second order with variable coefficients. Message 2. Boundary value problems with boundary conditions of the second and third kind

Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2017
We present the second message of the cycle from two articles where the rearrangement of the order of approximation of the matrix method of numerical integration depending on the degree in the Taylor’s polynomial expansion of solutions of boundary value ...
Vladimir N Maklakov
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Taming The Third Order Cumulant Approximation to Linear Optical Spectroscopy

The second order cumulant method offers a promising pathway to predicting optical properties in condensed phase systems. It allows for the computation of linear absorption spectra from excitation energy fluctuations sampled along molecular dynamics (MD ...
Luke, Allan, Tim, Zuehlsdorff
core   +1 more source

Excitation and breakup of [pi]+[pi]--atoms at high energies [PDF]

, 2003
The DIRAC collaboration at CERN currently aims at measuring the lifetime of pionium (π + π − -atoms) with an accuracy of 10%. This is a crucial test of Chiral Perturbation Theory which predicts the lifetime to be (2.9 ± 0.1) fs.
Schumann, Marc
core   +1 more source