Results 181 to 190 of about 72,832 (299)

Synthetic aptamer mechanoreceptors enable cell-specific force sensing and temporal control via DNA circuits. [PDF]

Nat Commun
Xu T, Sethi S, Drees C, Walther A.
europepmc   +1 more source

When Blood Proteins Reveal What Transcripts Miss: Immune Cell Priming and the Road to Prognostic Biomarkers in Lupus

Arthritis &Rheumatology, EarlyView.
Ioannis Parodis
wiley   +1 more source

Mimic, target, and adapt: Cell membrane‐coated nanoplatforms for precision and immune‐guided cancer treatment

BMEMat, EarlyView.
This Perspective explores the emerging landscape of cell membrane‐coated nanoparticles (CM‐NPs) as intelligent, immune‐compatible platforms for cancer therapy. Highlighting design strategies, translational challenges, and competitive positioning, it outlines how integrating biomimetic targeting with advanced analytical and manufacturing tools could ...
A. K. M. M. Alam, Xiaojun Cai, Malik Ihsan Ullah Khan, Robert Musiol, Quazi T. H. Shubhra   +4 more
wiley   +1 more source

A general strategy to enhance aptamer affinity by suppressing dissociation through symmetric assembly. [PDF]

Nucleic Acids Res
Zhang Z, Tian W, Gu J, Li J, Liu M, Soleymani L, Li Y.   +6 more
europepmc   +1 more source

Real time in vivo efficacy monitoring of desialylation and perforation enhanced immunotherapy of cancer

BMEMat, EarlyView.
A multifunctional nanomedicine is designed to engineer NK cells for enhanced cancer immunotherapy through perforation and desialylation, enabling real‐time monitoring of ATP and GrB levels for precise efficacy assessment. Abstract Efficient enhanced NK cell therapy is of critical importance in the immune treatment of cancer.
Yuanjiao Yang, Yuru Wang, Xuemei Li, Chaoyi Yang, Yuhui Yang, Yanyun Fang, Lin Ding, Yunlong Chen, Huangxian Ju   +8 more
wiley   +1 more source

From Selection to Use: Aptamers as Targeting Reagents in Hematology. [PDF]

Biomedicines
Albert B, Ebanks F, Gharagozloo K, Hai X, Ngu R, Munting S, McKeague M.   +6 more
europepmc   +1 more source

Paradigm shift in wearable bioelectronics: Drift‐free organic field‐effect transistor biosensors enabled by diode‐connected pairs

BMEMat, EarlyView.
Organic field‐effect transistor (OFET)‐based biosensors are promising for wearable technology due to their flexibility and low cost, but their susceptibility to signal drift from mechanical stress and environmental factors remains a challenge. Here, we highlight a novel strategy that eliminates these drifts through a fundamental redesign of the OFET ...
Yan Xu, Bin Yao, Jiahe Wang, Yichun Ding
wiley   +1 more source

A Computational Modeling for Reconfigurable Biosensors. [PDF]

Bionanoscience
Grasso R, Gonzalez-Medina JM, Barbruni GL, Carrara S.   +3 more
europepmc   +1 more source

Integrated spherical nucleic acid nanoreactor mobilizes targeted PD‐L1 proteolysis and cuproptosis for robust breast cancer immunotherapy

BMEMat, EarlyView.
This study provides an integrated spherical nucleic acid nanoreactor (denoted as AMCuD) for targeted PD‐L1 degradation and chemo‐dynamically enhanced cuproptosis to synergically elicit robust immunotherapy against the triple‐negative breast cancer (TNBC) growth, recurrence and metastasis.
Ningxi Li, Honglin Huang, Qianyi Zeng, Li Zeng, Ziman Yang, Jinyang Shen, Shun Li, Hong Yang, Yiyao Liu, Chunhui Wu   +9 more
wiley   +1 more source

New Player in the Field of Glioblastoma Therapy: EGFRvIII-Specific Gol1 Aptamer Shows a Great Therapeutic Potential. [PDF]

Pharmaceutics
Dzarieva F, Pavlova S, Fab L, Shamadykova D, Revishchin A, Alekseeva A, Kopylov A, Pronin I, Pavlova G.   +8 more
europepmc   +1 more source