Results 1 to 10 of about 12,731 (219)
RAPID-SELEX for RNA aptamers. [PDF]
PLoS ONE, 2013 Aptamers are high-affinity ligands selected from DNA or RNA libraries via SELEX, a repetitive in vitro process of sequential selection and amplification steps.
Kylan Szeto +7 more
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Inside the Black Box: What Makes SELEX Better?
Molecules, 2019 Aptamers are small oligonucleotides that are capable of binding specifically to a target, with impressive potential for analysis, diagnostics, and therapeutics applications.
Natalia Komarova, Alexander Kuznetsov
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Sensors, 2015 Whole-cell Systemic Evolution of Ligands by Exponential enrichment (SELEX) is the process by which aptamers specific to target cells are developed. Aptamers selected by whole-cell SELEX have high affinity and specificity for bacterial surface molecules ...
Jihea Moon +4 more
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Advantages, applications, and future directions of in vivo aptamer SELEX: A review
Molecular Therapy: Nucleic AcidsIn vivo systematic evolution of ligands by exponential enrichment (SELEX) emerged as a transformative technique for directly identifying aptamers within living organisms.
Minchuan Lyu +4 more
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From cell-SELEX to tissue-SELEX for targeted drug delivery and aptamer nanomedicine
Advanced Drug Delivery ReviewsAptamers are nucleic acid-based ligands that can selectively bind to target molecules. Because of their unique target-binding properties, the use of aptamers for targeting cell surface molecules has attracted broad research interest. The field has evolved from selecting aptamers against purified surface proteins to using whole cells (cell-SELEX) as ...
Ka-Ying Wong +2 more
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The Potential Use of Aptamers in The Process of Drug Development [PDF]
Pharmaceutical Sciences, 2021 Single-stranded nucleic acids can fold and create unique 3-dimensional structures when interacting with other molecules. The unique structure can achieve high specificity and affinity for the particular target.
Tooba Gholikhani +3 more
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Acta Biomedica Scientifica, 2022 Background. Aptamers are small single-stranded DNA or RNA molecules that have an affinity for a specific target molecule. The main method of aptamers construction is the technology of systematic evolution of ligands with exponential enrichment (SELEX ...
I. S. Solovarov +4 more
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Frontiers in Bioscience-Landmark, 2022 Background: Diazinon is a widely used organophosphorus neurotoxic insecticide. It is a common environmental contaminant and a hazardous agri-waste. Its detection is critical to control entry into food systems and protect the environment. Methods: In this
Mai-Huong Thi Can +11 more
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Surveillance Unattended Foliage Penetrating Radar for Border Control and Homeland Protection [PDF]
TransNav, 2013 The increasing request for safety, security and environment protection at local and national level reveal the deficiency of the traditional surveillance and control centers to satisfy the needs and requirements of modern border control systems for ...
Felicia Amato +3 more
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CyTA - Journal of Food, 2021 Deoxynivalenol (DON) is a mycotoxin commonly found in cereals and animal feeds, which also is a carcinogen easily soluble in water. So it has drawn considerable interest in food safety.
Mingwei Qin +6 more
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