Results 21 to 30 of about 12,731 (219)
Datenanalyse von Hochdurchsatz SELEX Experimenten mit komplexen Zielstrukturen [PDF]
, 2021 In dieser Arbeit werden aktuelle bioinformatische Tools und Methoden zurAnalyse von HT-SELEX Experimenten umgesetzt. SELEX (Systematic Evolution of Ligands by Exponential Enrichment) ist ein in vitro Prozess derzur sequentiellen evolutionären Entwicklung
Aschl, Ulrich Josef
core +1 more source
Aptamers in Therapeutics [PDF]
Journal of Clinical and Diagnostic Research, 2016 Aptamers are single strand DNA or RNA molecules, selected by an iterative process known as Systematic Evolution of Ligands by Exponential Enrichment (SELEX).
Abhishek Parashar
doaj +1 more source
Synthetic biology tools to promote the folding and function of RNA aptamers in mammalian cells
RNA Biology, 2023 RNA aptamers are structured RNAs that can bind to diverse ligands, including proteins, metabolites, and other small molecules. RNA aptamers are widely used as in vitro affinity reagents.
Qian Hou, Samie R. Jaffrey
doaj +1 more source
A mathematical analysis of SELEX [PDF]
Computational Biology and Chemistry, 2007 Systematic evolution of ligands by exponential enrichment (SELEX) is a procedure by which a mixture of nucleic acids that vary in sequence can be separated into pure components with the goal of isolating those with specific biochemical activities. The basic idea is to combine the mixture with a specific target molecule and then separate the target-NA ...
Howard A. Levine, Marit Nilsen-Hamilton
openaire +2 more sources
AIP Conference Proceedings, 2000 Talk given at the Session honoring Leon Lederman at the VII Mexican Workshop on Particles and Fields, Merida, Mexico, November 10-17, 1999.
openaire +2 more sources
Recent results from selex [PDF]
Nuclear Physics B - Proceedings Supplements, 2001 Preliminary results on asymmetry for Lc produced by Sigma-,pi- and p beams at xf>0.2 and precise measurements of the Lc,D0 and Ds lifetimes are presented.
SELEX Collaboration, Iori, M.
openaire +4 more sources
An improved SELEX-Seq strategy for characterizing DNA-binding specificity of transcription factor: NF-κB as an example. [PDF]
PLoS ONE, 2013 SELEX-Seq is now the optimal high-throughput technique for characterizing DNA-binding specificities of transcription factors. In this study, we introduced an improved EMSA-based SELEX-Seq strategy with several advantages.
Guangming Gu +4 more
doaj +1 more source
The application of Aptamer in biomarker discovery
Biomarker Research, 2023 Biomarkers are detectable molecules that can reflect specific physiological states of cells, organs, and organisms and therefore be regarded as indicators for specific diseases. And the discovery of biomarkers plays an essential role in cancer management
Yongshu Li +11 more
doaj +1 more source
e-Navigation and Future Trend in Navigation [PDF]
TransNav, 2011 The International Maritime Organization (IMO) adopted the following definition of e-Navigation: ?e-Navigation is the harmonised collection, integration, exchange, presentation and analysis of maritime information onboard and ashore by electronic means to
Felicia Amato +3 more
doaj
Aptamers for mycotoxin recognition in food: Recent advances and future considerations
Advanced Agrochem, 2023 The contamination of mycotoxin in food has posed a serious threat to human health and safety. Accurate detection of mycotoxins provides a strong guarantee for food safety.
Peng Fang, Hao Qu, Yu Mao, Lei Zheng
doaj +1 more source