Results 21 to 30 of about 9,625 (180)
An improved SELEX-Seq strategy for characterizing DNA-binding specificity of transcription factor: NF-κB as an example. [PDF]
SELEX-Seq is now the optimal high-throughput technique for characterizing DNA-binding specificities of transcription factors. In this study, we introduced an improved EMSA-based SELEX-Seq strategy with several advantages.
Guangming Gu +4 more
doaj +1 more source
Aptamers for mycotoxin recognition in food: Recent advances and future considerations
The contamination of mycotoxin in food has posed a serious threat to human health and safety. Accurate detection of mycotoxins provides a strong guarantee for food safety.
Peng Fang, Hao Qu, Yu Mao, Lei Zheng
doaj +1 more source
Aptamers are molecules identified from large combinatorial nucleic acid libraries by their high affinity to target molecules. Due to a variety of desired properties, aptamers are attractive alternatives to antibodies in molecular biology and medical applications.
openaire +2 more sources
Ka Band Phase Locked Loop Oscillator Dielectric Resonator Oscillator for Satellite EHF Band Receiver
This paper describes the design and fabrication of a Ka Band PLL DRO having a fundamental oscillation frequency of 19.250 GHz, used as local oscillator in the low-noise block of a down converter (LNB) for an EHF band receiver.
S. Coco +3 more
doaj +1 more source
Principle of Emulsion PCR and Its Applications in Biotechnology
Emulsion polymerase chain reaction (PCR) is performed on compartmentalized DNA, allowing a large number of PCR reactions to be carried out in parallel. Emulsion PCR has unique advantages in DNA amplification.
Changhoon Chai
doaj +1 more source
Multi-Output Power Converter, Operated from a Regulated Input Bus, for the Sireus Rate Sensor
This paper describes a DC to DC converter designed to meet the power supply requirements of the SiREUS Coarse Rate Sensor (CRS) which is a 3-axis MEMS Rate Sensor (MRS) that uses a resonating ring gyro and will be used in different ESA missions.
Torrecilla Marcos Compadre +3 more
doaj +1 more source
FSBC: fast string-based clustering for HT-SELEX data
Background The combination of systematic evolution of ligands by exponential enrichment (SELEX) and deep sequencing is termed high-throughput (HT)-SELEX, which enables searching aptamer candidates from a massive amount of oligonucleotide sequences.
Shintaro Kato +7 more
doaj +1 more source
Rationally designed DNA multivalent aptamers direct specific protein binding to drive self‐assembly into protein‐DNA frameworks (PDFs). Structurally defined protein‐aptamer interfaces organize proteins into triangles, linear and ladderlike chains, and periodic two‐dimensional arrays, enabling precise control over orientation, connectivity, and overall ...
Zhe Zhang +11 more
wiley +2 more sources
Aptamers are a group of synthetic single-stranded nucleic acids. They are generated from a random library of single-stranded DNA or RNA by a technology named systematic evolution of ligands by exponential enrichment (SELEX). SELEX is a repetitive process
Zixuen Gan +7 more
doaj +1 more source
MetaboSense is a first‐of‐its‐kind microfluidic platform enabling continuous, in‐line monitoring of glucose and lactate during ex vivo lung perfusion. Combining a quantum dot–mediated aptamer assay with mixing, depletion, and optofluidic detection modules, it achieves 60–s temporal resolution and shows strong agreement with standard blood gas analyzers,
Sanjana Srikant +14 more
wiley +1 more source

