Results 21 to 30 of about 19,390 (205)

Complementary chain competition and fluorescence quenching detection of Deoxynivalenol and analytical applications using a novel aptamer

open access: yesCyTA - Journal of Food, 2021
Deoxynivalenol (DON) is a mycotoxin commonly found in cereals and animal feeds, which also is a carcinogen easily soluble in water. So it has drawn considerable interest in food safety.
Mingwei Qin   +6 more
doaj   +1 more source

Development of DNA aptamer selection approach based on membrane ultrafiltration of aptamer/target complex

open access: yesActa Biomedica Scientifica, 2022
Background. Aptamers are small single-stranded DNA or RNA molecules that have an affinity for a specific target molecule. The main method of aptamers construction is the technology of systematic evolution of ligands with exponential enrichment (SELEX ...
I. S. Solovarov   +4 more
doaj   +1 more source

Imaging the coupling of terahertz radiation to a high electron mobility transistor in the near-field [PDF]

open access: yesJournal of the European Optical Society-Rapid Publications, 2009
We used AlGaN/GaN high electron mobility transistors as room-temperature direct detectors of radiation at 0.15 THz from a free electron laser, hence 5 times higher than their cutoff frequency of 30 GHz.
Ortolani M.   +12 more
doaj   +1 more source

Imaging of Neurite Network with an Anti-L1CAM Aptamer Generated by Neurite-SELEX

open access: yes, 2018
Neurite outgrowth is the critical step of nervous development. Molecular probes against neurites are essential for evaluation of the nervous system development, compound neurotoxicity, and drug efficacy on nerve regeneration.
Linlin Wang (289071)   +7 more
core   +3 more sources

Datenanalyse von Hochdurchsatz SELEX Experimenten mit komplexen Zielstrukturen [PDF]

open access: yes, 2021
In dieser Arbeit werden aktuelle bioinformatische Tools und Methoden zurAnalyse von HT-SELEX Experimenten umgesetzt. SELEX (Systematic Evolution of Ligands by Exponential Enrichment) ist ein in vitro Prozess derzur sequentiellen evolutionären Entwicklung
Aschl, Ulrich Josef
core   +1 more source

Aptamers and antibodies: rivals or allies in cancer targeted therapy?

open access: yesExploration of Targeted Anti-tumor Therapy, 2021
The goal of an efficacious cancer therapy is to specifically target diseased cells at high accuracy while sparing normal, healthy cells. Over the past three decades, immunotherapy, based on the use of monoclonal antibodies (mAbs) directed against tumor ...
Lisa Agnello   +3 more
doaj   +1 more source

Aptamers in Therapeutics [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Aptamers are single strand DNA or RNA molecules, selected by an iterative process known as Systematic Evolution of Ligands by Exponential Enrichment (SELEX).
Abhishek Parashar
doaj   +1 more source

Synthetic biology tools to promote the folding and function of RNA aptamers in mammalian cells

open access: yesRNA Biology, 2023
RNA aptamers are structured RNAs that can bind to diverse ligands, including proteins, metabolites, and other small molecules. RNA aptamers are widely used as in vitro affinity reagents.
Qian Hou, Samie R. Jaffrey
doaj   +1 more source

SELEX: Critical factors and optimization strategies for successful aptamer selection

open access: yesBiotechnology and applied biochemistry, 2021
Within the last decade, the application range of aptamers in biochemistry and medicine has expanded rapidly. More than just a replacement for antibodies, these intrinsically structured RNA‐ or DNA‐oligonucleotides show great potential for utilization in ...
Michael Kohlberger, G. Gadermaier
semanticscholar   +1 more source

e-Navigation and Future Trend in Navigation [PDF]

open access: yesTransNav, 2011
The International Maritime Organization (IMO) adopted the following definition of e-Navigation: ?e-Navigation is the harmonised collection, integration, exchange, presentation and analysis of maritime information onboard and ashore by electronic means to
Felicia Amato   +3 more
doaj  

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