Results 31 to 40 of about 19,390 (205)
The application of Aptamer in biomarker discovery
Biomarker Research, 2023 Biomarkers are detectable molecules that can reflect specific physiological states of cells, organs, and organisms and therefore be regarded as indicators for specific diseases. And the discovery of biomarkers plays an essential role in cancer management
Yongshu Li +11 more
doaj +1 more source
Selection of allosteric dnazymes that can sense phenylalanine by expression-SELEX
Nucleic Acids Research, 2023 Aptamers are ligand-binding RNA or DNA molecules and have been widely examined as biosensors, diagnostic tools, and therapeutic agents. The application of aptamers as biosensors commonly requires an expression platform to produce a signal to report the ...
Binfen Chen +5 more
semanticscholar +1 more source
RNA Capture-SELEX on Streptavidin Magnetic Beads
, 2023 SELEX has enabled the selection of aptamers, nucleic acids that can bind a defined ligand, in some cases with exceptionally high affinity and specificity. The SELEX protocol has been adapted many times to fit a variety of needs.
Kraus, Leon, Suess, Beatrix
core +1 more source
An improved SELEX-Seq strategy for characterizing DNA-binding specificity of transcription factor: NF-κB as an example. [PDF]
PLoS ONE, 2013 SELEX-Seq is now the optimal high-throughput technique for characterizing DNA-binding specificities of transcription factors. In this study, we introduced an improved EMSA-based SELEX-Seq strategy with several advantages.
Guangming Gu +4 more
doaj +1 more source
Angewandte Chemie, EarlyView.Protein‐binding aptamers remain poorly understood compared to their small‐molecule counterparts. Using green fluorescent protein (GFP) variants as a tractable model system, we show how subtle changes in protein surface composition and divalent metal ions reshape aptamer selection, specificity, and binding.
Stefen Stangherlin +8 more
wiley +2 more sources
Aptamers for mycotoxin recognition in food: Recent advances and future considerations
Advanced Agrochem, 2023 The contamination of mycotoxin in food has posed a serious threat to human health and safety. Accurate detection of mycotoxins provides a strong guarantee for food safety.
Peng Fang, Hao Qu, Yu Mao, Lei Zheng
doaj +1 more source
Matrix‐Activated Aptamer Sensors for Human Serum Analysis
Angewandte Chemie, EarlyView.The sample self‐analyzes: The predominant serum proteins, albumin and immunoglobulin G, were leveraged to activate the response of fluorescent aptamer probes within the biological matrix. The fluorescence‐anisotropy‐based sensing platform demonstrated both performance and consistency for the direct detection of small molecules in serum‐rich samples ...
Amandine Barbaroux +8 more
wiley +2 more sources
Ka Band Phase Locked Loop Oscillator Dielectric Resonator Oscillator for Satellite EHF Band Receiver
Active and Passive Electronic Components, 2008 This paper describes the design and fabrication of a Ka Band PLL DRO having a fundamental oscillation frequency of 19.250 GHz, used as local oscillator in the low-noise block of a down converter (LNB) for an EHF band receiver.
S. Coco +3 more
doaj +1 more source
Principle of Emulsion PCR and Its Applications in Biotechnology
Journal of Animal Reproduction and Biotechnology, 2019 Emulsion polymerase chain reaction (PCR) is performed on compartmentalized DNA, allowing a large number of PCR reactions to be carried out in parallel. Emulsion PCR has unique advantages in DNA amplification.
Changhoon Chai
doaj +1 more source
Multi-Output Power Converter, Operated from a Regulated Input Bus, for the Sireus Rate Sensor
E3S Web of Conferences, 2017 This paper describes a DC to DC converter designed to meet the power supply requirements of the SiREUS Coarse Rate Sensor (CRS) which is a 3-axis MEMS Rate Sensor (MRS) that uses a resonating ring gyro and will be used in different ESA missions.
Torrecilla Marcos Compadre +3 more
doaj +1 more source