Results 11 to 20 of about 20,710 (205)

Selex [PDF]

open access: yesAIP Conference Proceedings, 2000
A summary of the path which lead to a high energy physics group at Instituto de Fisica de la Universidad Autonoma de San Luis Potosi is presented. This group is the result of the initial push made by Leon Lederman at the beginning of the 80's.Comment ...
Morelos, A.
core   +2 more sources

RAPID-SELEX for RNA aptamers. [PDF]

open access: yesPLoS ONE, 2013
Aptamers are high-affinity ligands selected from DNA or RNA libraries via SELEX, a repetitive in vitro process of sequential selection and amplification steps.
Kylan Szeto   +7 more
doaj   +5 more sources

Recent results from selex [PDF]

open access: yesNuclear Physics B - Proceedings Supplements, 2001
Preliminary results on asymmetry for Lc produced by Sigma-,pi- and p beams at xf>0.2 and precise measurements of the Lc,D0 and Ds lifetimes are presented.
SELEX Collaboration, Iori, M.
openaire   +4 more sources

Aptamers in Therapeutics [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Aptamers are single strand DNA or RNA molecules, selected by an iterative process known as Systematic Evolution of Ligands by Exponential Enrichment (SELEX).
Abhishek Parashar
doaj   +1 more source

Synthetic biology tools to promote the folding and function of RNA aptamers in mammalian cells

open access: yesRNA Biology, 2023
RNA aptamers are structured RNAs that can bind to diverse ligands, including proteins, metabolites, and other small molecules. RNA aptamers are widely used as in vitro affinity reagents.
Qian Hou, Samie R. Jaffrey
doaj   +1 more source

Libraries for genomic SELEX [PDF]

open access: yesNucleic Acids Research, 1997
An increasing number of proteins are being identified that regulate gene expression by binding specific nucleic acidsin vivo. A method termed genomic SELEX facilitates the rapid identification of networks of protein-nucleic acid interactions by identifying within the genomic sequences of an organism the highest affinity sites for any protein of the ...
B S, Singer   +3 more
openaire   +2 more sources

Experimental Techniques [PDF]

open access: yes, 1999
In this course we will give examples for experimental techniques used in particle physics experiments. After a short introduction, we will discuss applications in silicon microstrip detectors, wire chambers, and single photon detection in Ring Imaging ...
Engelfried, J.
core   +3 more sources

An improved SELEX-Seq strategy for characterizing DNA-binding specificity of transcription factor: NF-κB as an example. [PDF]

open access: yesPLoS ONE, 2013
SELEX-Seq is now the optimal high-throughput technique for characterizing DNA-binding specificities of transcription factors. In this study, we introduced an improved EMSA-based SELEX-Seq strategy with several advantages.
Guangming Gu   +4 more
doaj   +1 more source

Capture-SELEX: Selection Strategy, Aptamer Identification, and Biosensing Application

open access: yesBiosensors, 2022
Small-molecule contaminants, such as antibiotics, pesticides, and plasticizers, have emerged as one of the substances most detrimental to human health and the environment.
Sin Yu Lam, Hill Lam Lau, Chun Kit Kwok
doaj   +1 more source

Cell-SELEX Technology [PDF]

open access: yesBioResearch Open Access, 2012
Aptamers are molecules identified from large combinatorial nucleic acid libraries by their high affinity to target molecules. Due to a variety of desired properties, aptamers are attractive alternatives to antibodies in molecular biology and medical applications.
openaire   +2 more sources

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