Results 11 to 20 of about 9,625 (180)
Libraries for genomic SELEX [PDF]
Nucleic Acids Research, 1997 An increasing number of proteins are being identified that regulate gene expression by binding specific nucleic acidsin vivo. A method termed genomic SELEX facilitates the rapid identification of networks of protein-nucleic acid interactions by identifying within the genomic sequences of an organism the highest affinity sites for any protein of the ...
B S, Singer +3 more
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Aptamers and antibodies: rivals or allies in cancer targeted therapy?
Exploration of Targeted Anti-tumor Therapy, 2021 The goal of an efficacious cancer therapy is to specifically target diseased cells at high accuracy while sparing normal, healthy cells. Over the past three decades, immunotherapy, based on the use of monoclonal antibodies (mAbs) directed against tumor ...
Lisa Agnello +3 more
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Aptamers in Therapeutics [PDF]
Journal of Clinical and Diagnostic Research, 2016 Aptamers are single strand DNA or RNA molecules, selected by an iterative process known as Systematic Evolution of Ligands by Exponential Enrichment (SELEX).
Abhishek Parashar
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Synthetic biology tools to promote the folding and function of RNA aptamers in mammalian cells
RNA Biology, 2023 RNA aptamers are structured RNAs that can bind to diverse ligands, including proteins, metabolites, and other small molecules. RNA aptamers are widely used as in vitro affinity reagents.
Qian Hou, Samie R. Jaffrey
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AIP Conference Proceedings, 2000 Talk given at the Session honoring Leon Lederman at the VII Mexican Workshop on Particles and Fields, Merida, Mexico, November 10-17, 1999.
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A mathematical analysis of SELEX [PDF]
Computational Biology and Chemistry, 2007 Systematic evolution of ligands by exponential enrichment (SELEX) is a procedure by which a mixture of nucleic acids that vary in sequence can be separated into pure components with the goal of isolating those with specific biochemical activities. The basic idea is to combine the mixture with a specific target molecule and then separate the target-NA ...
Howard A. Levine, Marit Nilsen-Hamilton
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Recent results from selex [PDF]
Nuclear Physics B - Proceedings Supplements, 2001 Preliminary results on asymmetry for Lc produced by Sigma-,pi- and p beams at xf>0.2 and precise measurements of the Lc,D0 and Ds lifetimes are presented.
SELEX Collaboration, Iori, M.
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The application of Aptamer in biomarker discovery
Biomarker Research, 2023 Biomarkers are detectable molecules that can reflect specific physiological states of cells, organs, and organisms and therefore be regarded as indicators for specific diseases. And the discovery of biomarkers plays an essential role in cancer management
Yongshu Li +11 more
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Capture-SELEX: Selection Strategy, Aptamer Identification, and Biosensing Application
Biosensors, 2022 Small-molecule contaminants, such as antibiotics, pesticides, and plasticizers, have emerged as one of the substances most detrimental to human health and the environment.
Sin Yu Lam, Hill Lam Lau, Chun Kit Kwok
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e-Navigation and Future Trend in Navigation [PDF]
TransNav, 2011 The International Maritime Organization (IMO) adopted the following definition of e-Navigation: ?e-Navigation is the harmonised collection, integration, exchange, presentation and analysis of maritime information onboard and ashore by electronic means to
Felicia Amato +3 more
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