Results 291 to 300 of about 78,567 (340)

Discovery of the High-Affinity Aptamer for Candidalysin Using a Dual-Mode Colorimetric-SERS Platform. [PDF]

open access: yesBiosensors (Basel)
Sun Y   +8 more
europepmc   +1 more source

Affinity Maturation of a Fentanyl Aptamer by Motif-SELEX. [PDF]

open access: yesJACS Au
Alkhamis O   +6 more
europepmc   +1 more source

Aptamers as therapeutics [PDF]

open access: yesNature Reviews Drug Discovery, 2010
Nucleic acid aptamers can be selected from pools of random-sequence oligonucleotides to bind a wide range of biomedically relevant proteins with affinities and specificities that are comparable to antibodies. Aptamers exhibit significant advantages relative to protein therapeutics in terms of size, synthetic accessibility and modification by medicinal ...
Anthony D Keefe, Andrew D Ellington
exaly   +3 more sources
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Aptamer chemistry

Advanced Drug Delivery Reviews, 2018
Aptamers are single-stranded DNA or RNA molecules capable of tightly binding to specific targets. These functional nucleic acids are obtained by an in vitro Darwinian evolution method coined SELEX (Systematic Evolution of Ligands by EXponential enrichment).
Röthlisberger, Pascal   +1 more
openaire   +3 more sources

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