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Aptamer-linked immobilized sorbent assay for detection of VP1 of foot and mouth disease virus serotype O. [PDF]
Quintela IA +4 more
europepmc +1 more source
Listeria monocytogenes detection assay via aptamer-functionalized magnetic bead enrichment coupled with RPA-CRISPR/Cas12a lateral flow strips. [PDF]
Wang H +11 more
europepmc +1 more source
Discovery of the High-Affinity Aptamer for Candidalysin Using a Dual-Mode Colorimetric-SERS Platform. [PDF]
Sun Y +8 more
europepmc +1 more source
Affinity Maturation of a Fentanyl Aptamer by Motif-SELEX. [PDF]
Alkhamis O +6 more
europepmc +1 more source
Aptamers as therapeutics [PDF]
Nucleic acid aptamers can be selected from pools of random-sequence oligonucleotides to bind a wide range of biomedically relevant proteins with affinities and specificities that are comparable to antibodies. Aptamers exhibit significant advantages relative to protein therapeutics in terms of size, synthetic accessibility and modification by medicinal ...
Anthony D Keefe, Andrew D Ellington
exaly +3 more sources
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Advanced Drug Delivery Reviews, 2018
Aptamers are single-stranded DNA or RNA molecules capable of tightly binding to specific targets. These functional nucleic acids are obtained by an in vitro Darwinian evolution method coined SELEX (Systematic Evolution of Ligands by EXponential enrichment).
Röthlisberger, Pascal +1 more
openaire +3 more sources
Aptamers are single-stranded DNA or RNA molecules capable of tightly binding to specific targets. These functional nucleic acids are obtained by an in vitro Darwinian evolution method coined SELEX (Systematic Evolution of Ligands by EXponential enrichment).
Röthlisberger, Pascal +1 more
openaire +3 more sources

