Using weighted harmonic mean for prediction of APTT in the mixing test
Thrombosis Update, 2022 Background: The mixing test of activated partial thromboplastin time (APTT) is used for differentiating factor deficiency (FD), lupus anticoagulant (LAC), and acquired hemophilia A (AHA).
Mitsuhiro Uchiba, Masao Matsuoka
doaj +2 more sources
In-house chromogenic anti-factor Xa assay: development, validation, and identification of factors predicting APTT discordance [PDF]
Frontiers in MedicineBackgroundActivated partial thromboplastin time (APTT) is the conventional test for monitoring unfractionated heparin (UFH) therapy, but discordance with anti-factor Xa results frequently occurs in clinical practice, potentially leading to suboptimal ...
Lin Sun +7 more
doaj +2 more sources
Determination of APTT factor sensitivity – the misguiding guideline [PDF]
International Journal of Laboratory Hematology, 2013 INTRODUCTION: The Clinical and Laboratory Standards Institute (CLSI) has produced a guideline detailing how to determine the activated partial thromboplastin time's (APTT) sensitivity to clotting factor deficiencies, by mixing normal and deficient ...
Steve Kitchen
exaly +4 more sources
The relationship between different anticoagulation monitoring indicators and heparin doses in adult patients with extracorporeal cardiopulmonary resuscitation [PDF]
Frontiers in Cardiovascular MedicineObjectivesAchieving optimal systemic anticoagulation in patients undergoing extracorporeal membrane oxygenation (ECMO) requires precise titration, posing a significant clinical challenge.
Jiali Yao +5 more
doaj +2 more sources
Dose response of nafamostat mesylate for anticoagulation monitoring in pediatric critical care during continuous venovenous hemodiafiltration [PDF]
Scientific ReportsNafamostat mesylate (NM) is increasingly used as an alternative anticoagulant during continuous venovenous hemodiafiltration (CVVHDF) in pediatric intensive care, especially when unfractionated heparin or regional citrate is contraindicated.
Sujin Lee, Jongyoon Kim, Bongjin Lee
doaj +2 more sources
Investigation of sensitivity for coagulation factor deficiency in APTT and PT: how to perform it? [PDF]
Clinical Chemistry and Laboratory Medicine, 2016 Katrien Devreese
exaly +3 more sources
Marine Drugs, 2023 Fucosylated glycosaminoglycans (FGs) derived from sea cucumbers exhibit potent intrinsic Xase (iXase) inhibition, anticoagulation, and antithrombosis. Plasma activated partial thromboplastin time (APTT), a widely used screening test worldwide, is crucial
Huifang Sun +9 more
doaj +1 more source
Isolated Prolongation of Activated Partial Thromboplastin Time: Not Just Bleeding Risk!
Medicina, 2023 Activated partial thromboplastin time (aPTT) is a fundamental screening test for coagulation disturbances. An increased aPTT ratio is quite common in clinical practice.
Rita Carlotta Santoro +3 more
doaj +1 more source
Comparison of Diagon Coag XL and Cobas t 511 analyzers
International Journal of Medical Biochemistry, 2022 INTRODUCTION: We compared prothrombin time (PT), activated partial thromboplastin time (aPTT), fibrinogen, and Ddimer test results measured using the Diagon Coag XL coagulation analyzer with Cobas t 511 analyzer.
Berrak Güven, Ismail Benice, Murat Can
doaj +1 more source
Indian Journal of Pathology and Microbiology, 2020 Background: Thrombophilia is a hypercoagulable state characterized by increased venous thrombosis. The most common cause of heritable thrombophilia is Factor V Leiden (FVR506Q) homozygous state, with a relative risk of 10–80 times as compared to normal ...
Mirza Asif Baig
doaj +1 more source