Results 221 to 230 of about 42,047 (260)

Reducing unnecessary testing in the emergency department: The case for INR and aPTT

CJEM, 2020
ABSTRACTObjectiveRoutine coagulation testing is rarely indicated in the emergency department. Our goal is to determine the combined effects of uncoupling routine coagulation testing (i.e., international normalized ratio [INR]; activated partial thromboplastin time [aPTT]), disseminating an educational module, and implementing a clinical decision ...
Davy Tawadrous, Sarah Detombe, Drew Thompson, Melanie Columbus, Kristine Van Aarsen, Terry Skoretz   +5 more
openaire   +2 more sources

Reflex factor coagulation testing in patients with an unexplained prolonged aPTT: An institutional retrospective review

International Journal of Laboratory Hematology, 2021
AbstractBackgroundWe aim to determine the clinical utility of reflex coagulation investigations (RCI) for prolonged lupus insensitive activated partial thromboplastin time (aPTT) at our institution.MethodsWe retrospectively reviewed all potential RCI (lupus insensitive aPTT of ≥32s) from April 2014 to June 2019.
Eman M Mansory, Fadi Bahodi, Chai W. Phua   +2 more
openaire   +2 more sources

Testing for Passovoy Defect in Children with Prolonged Activated Partial Thromboplastin Time (APTT)

Journal of Pediatric Hematology/Oncology, 1996
To investigate the value of testing for Passovoy defect using the commercially available Passovoy trait plasma (PTP) in children with prolonged activated partial thromboplastin time (APTT).We studied 13 children with prolonged APTT that corrected in a 1:1 mix with normal human plasma but not with PTP.
A, Hayani, C R, Suarez, J E, Godwin, C, Blakemore   +3 more
openaire   +2 more sources

STANDARDIZATION OF THE APTT TEST CURRENT STATUS

Scandinavian Journal of Haematology, 1980
The partial thromboplastin time (PTT) which is used as an overall measure of the intrinsic clotting system, is the commonest coagulation test employed in routine laboratories apart from the prothrombin time. The main functions of the test are: 1. to screen intrinsic coagulation defects; 2. to control heparin administration; 3.
openaire   +2 more sources

Comparing Direct Thrombin Inhibitors Using aPTT, Ecarin Clotting Times, and Thrombin Inhibitor Management Testing

Annals of Pharmacotherapy, 2004
BACKGROUND: Patients with heparin-induced thrombocytopenia and thrombosis may be acutely anticoagulated with direct thrombin inhibitors (DTIs). The anticoagulation is typically monitored using the activated partial thromboplastin time (aPTT) or ecarin clotting time (ECT).
Robert C, Gosselin, Jeffrey H, King, Kim A, Janatpour, William E, Dager, Edward C, Larkin, John T, Owings   +5 more
openaire   +2 more sources

sj-docx-1-cat-10.1177_10760296231183427 - Supplemental material for Routine Lupus Anticoagulant Sensitive aPTT Testing Can Prevent Unnecessary LA Testing

2023
Supplemental material, sj-docx-1-cat-10.1177_10760296231183427 for Routine Lupus Anticoagulant Sensitive aPTT Testing Can Prevent Unnecessary LA Testing by Bob Smit, PhD, Francisca Hudig, PhD, Jan-Hendrik Venhuizen, MS, Saskia Haitjema, PhD, Maarten Limper, MD, PhD, Rolf Urbanus, PhD, and Albert Huisman, PhD in Clinical and Applied Thrombosis ...
Smit, Bob, Hudig, Francisca, Venhuizen, Jan-Hendrik, Haitjema, Saskia, Limper, Maarten, Urbanus, Rolf, Huisman, Albert   +6 more
openaire   +1 more source

Lupus Anticoagulant Testing: Activated Partial Thromboplastin Time (APTT) and Silica Clotting Time (SCT)

2017
Actvated partial thromboplastin time and its congener test Silica clotting time are used for the laboratory detection of lupus anticoagulants. Their performance consists of mixing test plasma with activators of the contact coagulation factors, phospholipids and calcium chloride, and recording the clotting time.
Armando, Tripodi, Veena, Chantarangkul
openaire   +2 more sources

[Analysis of APTT Mixing Test Results in Factor Ⅷ Inhibitor-Positive Hemophilia Patients].

Zhongguo shi yan xue ye xue za zhi, 2023
To analyze the results of activated partial thromboplastin time (APTT) mixing test in coagulation factor Ⅷ inhibitor-positive hemophilia patients, so as to increase the value of APTT mixing test in the screen of factor Ⅷ inhibitor.Eighty plasmas samples with different titers of coagulation factor Ⅷ inhibitors had been collected and diluted for routine ...
Li-Hua, Zhang, Zhi-Qiang, Xie, He, Zhuang, Mei-Hua, Wang, Ying-Ping, Cao   +4 more
openaire   +1 more source

[Study on usefulness of different APTT test kit in variable coagulopathy].

Rinsho byori. The Japanese journal of clinical pathology, 2008
A number of test kits are available for measuring activated partial thromboplastin time (APTT) and are used to screen for intrinsic coagulation reactions. However, results obtained with the same sample by different test kits often vary, causing confusion regarding potential hemostatic activity in the specimen.
Sumiyoshi, Naito, Masahiro, Ieko, Mika, Yoshida, Takashi, Tarumi, Toru, Nakabayashi, Hitoshi, Nishio, Tatsuya, Atsumi   +6 more
openaire   +1 more source

A-145 Evaluating clinician compliance with laboratory guidance for prolonged aPTT testing

Clinical Chemistry
Abstract Background Activated partial thromboplastin time (aPTT) is a test used to evaluate coagulation disorders and is frequently ordered in the preoperative setting. When a patient presents with a prolonged aPTT (=> 40 sec) without documented anticoagulant use, our laboratory performs a ...
Noemie Lavoie, Daniele Marceau, Andrée-Anne Houde   +2 more
openaire   +1 more source