Results 231 to 240 of about 42,047 (260)

How to Optimize Activated Partial Thromboplastin Time (APTT) Testing: Solutions to Establishing and Verifying Normal Reference Intervals and Assessing APTT Reagents for Sensitivity to Heparin, Lupus Anticoagulant, and Clotting Factors

Seminars in Thrombosis and Hemostasis, 2019
AbstractThe activated partial thromboplastin time (APTT) assay is a very common coagulation test, used for several reasons. The test is conventionally used for assessing the contact factor (intrinsic) pathway of blood coagulation, and thus for screening deficiencies in this pathway, most typically factors VIII, IX, and XI. The APTT is also sensitive to
Favaloro, Emmanuel J, Kershaw, Geoffrey, Mohammed, Soma, Lippi, Giuseppe   +3 more
openaire   +2 more sources

A comparison study of routine coagulation screening tests (PT and APTT) by three automated coagulation analyzers

International Journal of Medical Science and Public Health, 2016
Background: In recent times, growing coagulation test volume and constricted personnel budgets have enhanced interest in automated coagulation analyzers. Objective: (i) To compare the reliability of routine coagulation test [prothrombin time (PT) and activated partial thromboplastin time (APTT)] using mechanical, photo-optical, and nephelemetric ...
Nitinkumar Rathod, Sukesh Nair, Joy Mammen, Surinder Singh   +3 more
openaire   +1 more source

APTT: A screening test for hypercoagulability in type 2 diabetes mellitus patients

Medical Journal of Zambia, 2014
Background: Thrombosis is a common complication in Type 2 Diabetes Mellitus (T2DM). Prolonged APTT values have clinical relevance as an indicator of factor deficiency or the presence of coagulation inhibitors. However, there is mounting evidence that shortened APTT values in some cases may reflect a hypercoagulable state, which is potentially ...
Mwambungu, A, Kaile, T, Korolova, L, Kwenda, J, Marimo, C   +4 more
openaire   +1 more source

Verification of the guidelines for lupus anticoagulant detection: Usefulness of index for circulating anticoagulant in APTT mixing test

Thrombosis Research, 2014
Lupus anticoagulant (LA) is an antibody that interferes with one or more in vitro coagulation reactions, which are dependent on interactions with protein-phospholipid complexes. For LA diagnosis, a mixing test is considered useful for differentiating the inhibitor from a factor deficiency.
Osamu, Kumano, Masahiro, Ieko, Sumiyoshi, Naito, Mika, Yoshida, Nobuhiko, Takahashi, Takeshi, Suzuki, Takashi, Aoki   +6 more
openaire   +2 more sources

Coagulation Testing: Looking Beyond the PT and aPTT

2023
Mark T. Friedman, Kamille A. West, Peyman Bizargity, Kyle Annen, H. Deniz Gur, Timothy Hilbert   +5 more
openaire   +1 more source

Determining the cutoff value of the APTT mixing test for factor VIII inhibitor

Clinical Chemistry and Laboratory Medicine (CCLM), 2019
Ning, Tang, Yaopeng, Chen, Dengju, Li, Shiyu, Yin   +3 more
openaire   +2 more sources

Monitoring of Unfractionated Heparin Therapy in the Intensive Care Unit Using a Point-of-Care aPTT: A Comparative, Longitudinal Observational Study with Laboratory-Based aPTT and Anti-Xa Activity Measurement

Journal of Clinical Medicine, 2022
Benjamin Lardinois, Michael Hardy, Hugues Jacqmin   +2 more
exaly  

APTT and PT THE TESTS OF TIME

Nursing, 1986
openaire   +2 more sources

[The effect of factor VIII:C activity on the activated partial thromboplastin time (aPTT) in the dog. Adaptation of the aPTT as a screening test for canine hemophilia A?].

DTW. Deutsche tierarztliche Wochenschrift, 1993
The factor VIII:C-sensitivity of the aPTT in dogs was investigated for 2 different, commercially available reagents. For this purpose, 45 plasmas with a decreased factor VIII:C-activity, which were collected from haemophilic dogs (n = 10) at variable points of time of a substitution therapy were used.
openaire   +1 more source

The responsiveness of different APTT reagents to mild factor VIII, IX and XI deficiencies

International Journal of Laboratory Hematology, 2011
A E Bowyer, Steve Kitchen, Michael Makris   +2 more
exaly