Results 111 to 120 of about 796 (185)

Stability-indicating green HPLC method for fixed-dose tablets containing remogliflozin etabonate and teneligliptin: an AQbD approach

Drug Development and Industrial Pharmacy
In June 2021, the Central Drug Standards Control Organization approved a fixed-dose combination tablet containing remogliflozin etabonate (100 mg) and teneligliptin (10 mg) to manage type II diabetes. This study aims to develop a stability-indicating RP-HPLC method for quantifying remogliflozin etabonate and teneligliptin in tablet formulations via ...
Raj Patel, Rajendra Kotadiya
openaire   +2 more sources

AQBD BASED LC-UV METHOD FOR ASSESSMENT OF ANTIVIRAL DRUGS IN TERNARY MIXTURE

Rasayan Journal of Chemistry, 2021
J. R. Tulasi, A. Prameela Rani, Pani Kumar Durga Anumolu   +2 more
openaire   +1 more source

Stability-Indicating UPLC-PDA-QDa Methodology for Carvedilol and Felodipine in Fixed-Dose Combinations Using AQbD Principles

Scientia Pharmaceutica
The development of analytical procedures, in line with the recent regulatory requirements ICH Q2 (R2) and ICH Q14, is progressing, and it must be able to manage the entire life cycle of the methodology.
Jesús Alberto Afonso Urich, Viktoria Marko, Katharina Boehm, Raymar Andreina Lara Garcia, Anna Fedorko, Sharareh Salar-Behzadi, Dalibor Jeremic   +6 more
doaj   +1 more source

Assessment and Computational Estimation of Omeprazole and Levosulpiride Impurities in Fixed Dose Combination by AQbD Approach

Archives of Advanced Engineering Science
This study focuses on novel high-performance liquid chromatography (HPLC) method to simultaneously identify and quantify degradation products of esomeprazole and levosulpiride in capsule dosage form, enhancing analytical precision and reliability.
Vikram Gharge, Satish Jadhao, Balasaheb Jadhav, Pranav Bang, Gurudatt Hendge, Nayan Jadhav, Rutuja Mulik, Shubham Bhange, Laxman Ingole   +8 more
openaire   +1 more source

AQbD-guided stability indicating HPLC method for azelnidipine and chlorthalidone fixed-dose combination tablet: a green approach

Journal of Taibah University for Science
This study developed a stability-indicating RP-HPLC method for quantifying azelnidipine and chlorthalidone in fixed-dose formulations using Analytical Quality by Design (AQbD) principles.
Rajvi Agrawal, Rajendra Kotadiya
doaj   +1 more source

Implementation of Analytical Quality by Design (AQbD) approach to RP-HPLC method for dissolution testing

, 2015
Quality by Design (QbD) principles were implemented in RP-HPLC method development for the analysis of dissolution samples of immediate release film-coated tablets. Critical method variables and critical method attributes were identified. After the initial risk assessment, a DoE (design of experiments) study was performed to investigate the impact of ...
Pranjić, Josip, Radošević, Senka, Lusina Kregar, Maja   +2 more
openaire   +2 more sources

Development of eco-friendly and sustainable analytical methods for Ritonavir through white analytical chemistry and AQbD approach

Discover Chemistry
The present research study outlines the development and validation of a cost-effective, eco-sustainable, and robust analytical procedure for the quantitative estimation of Ritonavir in bulk and tablet dosage form using UV Spectrophotometry and Reverse ...
Vaibhav Sawale, Prafulla Sabale, Roshni Kunte, Vidya Sabale   +3 more
doaj   +1 more source

Analytical Quality by Design Driven Development and Validation of UV-Visible Spectrophotometric Method for Quantification of Xanthohumol in Bulk and Solid Lipid Nanoparticles. [PDF]

Turk J Pharm Sci, 2023
Vancha H, Tewari D, Kumar R, Govindaiah P, Mohd S, Singh SK, Gulati M.   +6 more
europepmc   +1 more source

Design Approach in RP-HPLC Method Development and Validation of Nirogacestat in its Pure and Pharmaceutical Dosage Form [PDF]

Aim: Nirogacestat is a selective γ-secretase inhibitor approved by the USFDA for the treatment of Desmoid Tumour. Objective: In this study, a reversed-phase high performance liquid chromatography (RP-HPLC) method was designed to analyze the concentration
Chandrasekar R, Sivagami B, Roshini M, Kumanan R, Sudha S, Sai Koteswar Sharma
core   +1 more source

Development of Analytical Quality by Design Compliant Chaotropic Chromatography Method for Ziprasidone and Its Five Impurities Determination. [PDF]

Pharmaceuticals (Basel), 2023
Rmandić M, Vasilić Đ, Rašević M, Zečević M, Otašević B, Protić A, Malenović A.   +6 more
europepmc   +1 more source