Results 91 to 100 of about 833 (196)
Journal of Saudi Chemical SocietyThe goal of this study was to use High performance liquid chromatography (HPLC) with an Analytical Quality by Design (AQbD) approach to measure the amount of caffeine in selected coffee samples available in the local Jazan market in Saudi Arabia.
Asim Najmi +9 more
doaj +1 more source
Model inversion and three-way decompositions in the analytical quality by design strategy for the determination of phthalates BY HS-SPME-GC-MS [PDF]
In this work, strategies within Analytical Quality by Design (AQbD) with tools of the Process Analytical Technology (PAT) were used in the development of a head space-solid phase microextraction-gas chromatography-mass spectrometry (HS-SPME-GC-MS ...
Herrero Gutiérrez, Ana +5 more
core +1 more source
Future Journal of Pharmaceutical SciencesBackground The Analytical Quality by Design (AQbD) methodology extends the application of Quality by Design (QbD) principles to the management of the analytical procedure life cycle, encompassing method creation, optimization, validation, and continuous ...
Mohana Vamsi Nuli +2 more
doaj +1 more source
Frontiers in Analytical ScienceIntroductionA reversed-phase high-performance liquid chromatographic (RP-HPLC) method was developed and validated for the quantitation of nevirapine (NVP) in bulk drug, commercial tablets, and niosome formulations using an Analytical Quality by Design ...
Bwalya A. Witika, Roderick B. Walker
doaj +1 more source
OPTIMIZING RP-HPLC TECHNIQUES FOR RELIABLE ANALYSIS OF DIABETES MEDICATIONS [PDF]
Introduction: A robust and precise RP-HPLC method was developed for the simultaneous quantification of Metformin, Vildagliptin, and Remogliflozin in pharmaceutical formulations, essential for managing Type 2 Diabetes Mellitus (T2DM).
Venkata sai suresh kumar sista* , Anjali jha, V LNSH Hari Haran. A, R S K Sharma , Anindita Chatterjee, G V Siva Prasad, K. Satyam Naidu, R. Sarada
core +2 more sources
Journal of Pharmaceutical and Biopharmaceutical ResearchUsing advanced scientific and risk-based approaches for analytical methods offers significant benefits. Quality by Design (QbD) is a systematic framework that emphasizes understanding and controlling both product and process elements. Adhering to the principles outlined in the ICH guidelines can considerably improve the quality of drug substances ...
Vivekanandan Kalaiselvan +3 more
openaire +1 more source
Development and Validation of a Stability Indicating Analytical Method for the Estimation of Gliclazide and Sitagliptin in Bulk Drugs and Tablet Dosage Forms by RP-UPLC: An Application of the Quality-by-Design Approach [PDF]
Sitagliptin and gliclazide are the active ingredients in OpdualagTM. A highly selective DPP-4 inhibitor, sitagliptin is thought to work in type 2 diabetics by delaying the inactivation of incretin hormones, which increases their concentration and ...
Nunsavathu, Sambasiva Naik +1 more
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OPTIMASI DAN VALIDASI METODE KLT-DENSITOMETRI PADA ANALISIS FARMASI : TINJAUAN KRITIS DAN STUDI KOMPARATIF [PDF]
Kromatografi Lapis Tipis (KLT) Densitometri atau High Performance Thin Layer Chromatography (HPTLC) tetap menjadi metode analisis instrumental yang vital, terutama di negara berkembang, karena efisiensi biaya dan kemampuannya menangani banyak sampel ...
Anggrainy, Dian Sari +6 more
core +1 more source
A REVIEW ON RECENT STRATEGIES IN AQbD APPROACH
Recent strategies in the Analytical Quality by Design (AQbD) approach have transformed the way analytical methods are developed, optimized, and controlled in pharmaceutical and regulatory environments. AQbD integrates scientific knowledge and risk-based strategies to ensure the consistent performance and quality of analytical methods throughout their ...
openaire +1 more source