Results 111 to 120 of about 833 (196)

Analytical quality by design (AQbD) approach for the simultaneous quantification of FDC in a cardiovascular drug by RP-HPLC method

Future Journal of Pharmaceutical Sciences
Background A sustainable and stability-indicating reversed-phase high-pressure liquid chromatography (RP-HPLC) method has been developed for the simultaneous estimation of chlorthalidone (CHL), Amlodipine (AML), and olmesartan medoxomil (OLM) in a ...
Varsha Thorat, Sudhakar Alave, Vijay Bagul   +2 more
doaj   +1 more source

Stability-Indicating UPLC-PDA-QDa Methodology for Carvedilol and Felodipine in Fixed-Dose Combinations Using AQbD Principles

Scientia Pharmaceutica
The development of analytical procedures, in line with the recent regulatory requirements ICH Q2 (R2) and ICH Q14, is progressing, and it must be able to manage the entire life cycle of the methodology.
Jesús Alberto Afonso Urich, Viktoria Marko, Katharina Boehm, Raymar Andreina Lara Garcia, Anna Fedorko, Sharareh Salar-Behzadi, Dalibor Jeremic   +6 more
doaj   +1 more source

AQbD-based development of a stability-indicating UHPLC-PDA-QDa method for triptorelin in parenteral formulations

Analytical Methods
A stability-indicating RP-UHPLC method was developed using AQbD principles for quantifying triptorelin in injectable suspensions as a pharmaceutical dosage form.
Jesús Alberto Afonso Urich, Viktoria Marko, Anna Fedorko, Dalibor Jeremic   +3 more
openaire   +2 more sources

Development of eco-friendly and sustainable analytical methods for Ritonavir through white analytical chemistry and AQbD approach

Discover Chemistry
The present research study outlines the development and validation of a cost-effective, eco-sustainable, and robust analytical procedure for the quantitative estimation of Ritonavir in bulk and tablet dosage form using UV Spectrophotometry and Reverse ...
Vaibhav Sawale, Prafulla Sabale, Roshni Kunte, Vidya Sabale   +3 more
doaj   +1 more source

Advancing relugolix analysis: A comparative study and AQbD-driven method optimization with stability testing

Journal of Applied Pharmaceutical Science
The current study aimed to develop a novel liquid chromatographic method based on analytical quality by design to analyze relugolix and its related substances. This study builds upon a comparative review of existing analytical methods, highlighting the absence of a pharmacopoeial standard for relugolix determination.
Priyanka Nagar, Arvind Kumar Sharma, Robin Kumar, Chhaya Chauhan, Rini Singhal, Minakshi Garg   +5 more
openaire   +1 more source

Analytical Quality by Design Driven Development and Validation of UV-Visible Spectrophotometric Method for Quantification of Xanthohumol in Bulk and Solid Lipid Nanoparticles. [PDF]

Turk J Pharm Sci, 2023
Vancha H, Tewari D, Kumar R, Govindaiah P, Mohd S, Singh SK, Gulati M.   +6 more
europepmc   +1 more source

AQBD BASED LC-UV METHOD FOR ASSESSMENT OF ANTIVIRAL DRUGS IN TERNARY MIXTURE

Rasayan Journal of Chemistry, 2021
J. R. Tulasi, A. Prameela Rani, Pani Kumar Durga Anumolu   +2 more
openaire   +1 more source

Development of Analytical Quality by Design Compliant Chaotropic Chromatography Method for Ziprasidone and Its Five Impurities Determination. [PDF]

Pharmaceuticals (Basel), 2023
Rmandić M, Vasilić Đ, Rašević M, Zečević M, Otašević B, Protić A, Malenović A.   +6 more
europepmc   +1 more source

Design Approach in RP-HPLC Method Development and Validation of Nirogacestat in its Pure and Pharmaceutical Dosage Form [PDF]

Aim: Nirogacestat is a selective γ-secretase inhibitor approved by the USFDA for the treatment of Desmoid Tumour. Objective: In this study, a reversed-phase high performance liquid chromatography (RP-HPLC) method was designed to analyze the concentration
Chandrasekar R, Sivagami B, Roshini M, Kumanan R, Sudha S, Sai Koteswar Sharma
core   +1 more source

From design space to green space: an analytical quality by design-assisted high-performance liquid chromatography method for the quantification of triple-combination antihypertensive drugs. [PDF]

BMC Chem
Yenduri S, Yogaraj P, Koppuravuri NP.
europepmc   +1 more source