Results 81 to 90 of about 325 (160)

Quality by design in public healthcare: a rapid development framework for future pandemics

Journal of Pharmacy & Pharmaceutical Sciences
The growing number of pandemics and emergencies traversing the world in recent decades has illustrated the vulnerability of the conventional pharmaceutical development process and the necessity of an efficient, robust, and patient-driven pandemic-ready ...
Niranjan Panda, Madhusudan Maity, Vijay Kotra, Bikash Ranjan Jena, Debashish Ghose, Gouri Sankar Jena   +5 more
doaj   +1 more source

A comprehensive RP-HPLC technique for analyzing disodium edetate and its degradation products in eye drops using AQbD and Six Sigma perspective

Reviews in Analytical Chemistry
The study presents the development of a novel, sustainable, and analytical quality by design (AQbD) driven RP-HPLC method to simultaneously identify disodium edetate in eye drops and its degradation products.
Alanazi Tahani Y. A., Alluhayb Abdullah H., Alsehli Bandar R., Binsaleh Ammena Y., Saleh Sayed M., Mohamed Mahmoud A.   +5 more
doaj   +1 more source

Systematic AQbD Approach to UPLC Method Development for Elacestrant and Pirtobrutinib

The evolution of pharmaceutical analysis has led to the integration of Analytical Quality by Design (AQbD). This strategic framework enhances the robustness, reliability, and regulatory compliance of analytical methods. This review focuses on the AQbD-based development and validation of a novel Ultra Performance Liquid Chromatography (UPLC) method for ...
openaire   +1 more source

Integrated Application of Risk Management Techniques in Developing an Analysis Method for Traditional Chinese Medicine: A Case Study of a Percolation Solution for Xiaochaihu Capsules

Chemosensors
Risk management should run through the entire process of method development, utilization, and maintenance. Based on the analytical quality by design (AQbD) concept, various integrated risk management techniques were used in this study to develop an ...
Mintong Zhao, Yanni Tai, Gelin Wu, Feng Ding, Haibin Qu, Xingchu Gong   +5 more
doaj   +1 more source

RP-HPLC method development and validation of Abacavir, Lamivudine and Zidovudine in combined pharmaceutical dosage by analytical QbD

Discover Chemistry
An accurate, precise, robust, and green RP-HPLC method was developed for assessment of three antiviral medications, namely Abacavir (ABA), Lamivudine (LAMI), and Zidovudine (ZIDO) in combined pharmaceutical dosage form by Analytical Quality by Design ...
Divyesh Vanparia, Ronak R. Dedania, Zarna R. Dedania   +2 more
doaj   +1 more source

Analytical Quality by Design (AQbD): Principles, Tools and Case Studies

Quality by Design is a systematic approach used in pharmaceutical development that builds product quality into the formulation and manufacturing processes from the outset. Although its adoption is increasing within the generic drug industry, many professionals are still not deeply familiar with its principles or terminology.
openaire   +1 more source

Analytical Quality by Design (AQbD): A Contemporary Framework for Pharmaceutical Analytical Development

Analytical Quality by Design (AQbD) is a systematic, science- and risk-based approach for developing robust, reliable, and regulatory-compliant analytical methods in the pharmaceutical industry. Unlike traditional trial-and-error approaches, AQbD builds quality into the method from the beginning through predefined objectives, scientific understanding ...
openaire   +3 more sources

Development of a quality by design based eco-friendly RP-HPLC method for Ticagrelor and Aspirin

Green Analytical Chemistry
Background: Ticagrelor (TICA) and Aspirin (ASP) are widely prevalent antiplatelet drugs. With growing focus on sustainable operations, there is a necessity for green and strong analytical procedures for their simultaneous estimation. Objective: To design
Shivani Jani, Ujashkumar Shah, Jayvadan Patel, Monika Dua   +3 more
doaj   +1 more source

Application of the quality by design (QbD) approach to the development and validation of analytical methods for the quantification of Lumateperone Tosylate as the bulk drug and capsule dosage form by HPLC

Future Journal of Pharmaceutical Sciences
Background The current studies involve the development of a liquid chromatographic method that is highly effective (HPLC) for the Lumateperone Tosylate method that is simple, rapid, accurate, precise, and economical, all made possible by analytical ...
Vasudha S. Bavadekar, Angha M. Joshi, Ujwala S. Desai   +2 more
doaj   +1 more source

Implementation of quality by design and green chemistry principles to validate the stability indicating method on UHPLC for the simultaneous quantification of Glycopyrronium, Fluticasone, Vilanterol in inhaled formulation

Green Analytical Chemistry
The combination of Glycopyrronium, Fluticasone, and Vilanterol is utilized to manage chronic obstructive pulmonary disease (COPD) and mitigate asthma symptoms.
Anitha L, Durga Prasad Beda
doaj   +1 more source