Development and validation of a UPLC-MS method for determination of atazanavir sulfate by the “analytical quality by design” approach [PDF]
, 2020 A UPLC-MS method for the estimation of atazanavir sulfate was developed using the “analytical quality by design” approach. The critical chromatographic quality attributes identified were retention time, theoretical plates and peak tailing.
CHANDAN RAVANDUR SHIVANNA +2 more
core +2 more sources
Hidden Q-structure and Lie 3-algebra for non-abelian superconformal models in six dimensions
, 2014 We disclose the mathematical structure underlying the gauge field sector of the recently constructed non-abelian superconformal models in six spacetime dimensions. This is a coupled system of 1-form, 2-form, and 3-form gauge fields.
Lavau, Sylvain +2 more
core +3 more sources
Improving the biopharmaceutical attributes of mangiferin using vitamin E-TPGS co-loaded self-assembled phosholipidic nano-mixed micellar systems [PDF]
, 2018 The current research work encompasses the development, characterization, and evaluation of self-assembled phospholipidic nano-mixed miceller system (SPNMS) of a poorly soluble BCS Class IV xanthone bioactive, mangiferin (Mgf) functionalized with co ...
Gaspar, Balan Louis +5 more
core +2 more sources
ChemistryOpen, Volume 15, Issue 5, May 2026.A sustainable reversed‐phase liquid chromatography method is developed for diltiazem analysis and pKadetermination. The study integrates green and white analytical chemistry frameworks to evaluate environmental impact and practicality. The Environmental, Performance, and Practicality Index is utilized as a comprehensive, holistic tool for the ...
Zehra Üstün +2 more
wiley +1 more source
PLoS ONE, 2018 The aim of this study was to present a novel analytical quality by design (AQbD) approach for developing an HPLC method to analyze herbal extracts.
Jingyuan Shao +4 more
doaj +1 more source
Application of quality-by-design approach in the analytical method development for quantification of sugars in sugarcane honey by reversed-phase liquid chromatography [PDF]
, 2020 Produced in Madeira Island from regional sugarcane cultivars through a traditional manufacturing and storage process, sugarcane honey (SCH) is a black syrup recognized by its excellent quality.
Câmara, José S. +4 more
core +1 more source
A new approach based on inversion of a partial least squares model searching for a preset analytical target profile. Application to the determination of five bisphenols by liquid chromatography with diode array detector [PDF]
, 2021 The paper shows a procedure for selecting the control method parameters (factors) to obtain a preset ‘analytical target profile’ when a liquid chromatographic technique is going to be carried out for the simultaneous determination of five bisphenols ...
Arce Antón, Mar +5 more
core +1 more source
Регуляторные исследования и экспертиза лекарственных средствINTRODUCTION. In 2023, the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) published a new Guideline on Analytical Procedure Development (ICH Q14) and a revised version of the Guideline on ...
A. V. Fetisova +4 more
doaj +1 more source
Constraints on Modified Gravity Models from White Dwarfs
, 2017 Modified gravity theories can introduce modifications to the Poisson equation in the Newtonian limit. As a result, we expect to see interesting features of these modifications inside stellar objects.
Banerjee, Srimanta +2 more
core +1 more source
A systematic AQbD approach for optimization of the most influential experimental parameters on analysis of fish spoilage-related volatile amines [PDF]
, 2020 The volatile amines trimethylamine (TMA) and dimethylamine (DMA) could be used as important spoilage indices for seafood products, assisting in the determination of the rejection period.
Câmara, José S. +3 more
core +1 more source