Results 71 to 80 of about 325 (160)

A-QbD-based green RP-HPLC method for estimation of rivaroxaban in pharmaceutical dosage forms

Discover Chemistry
This work reports the Analytical Quality by Design (AQbD) based green RP-HPLC method for Rivaroxaban, aimed at delivering a sustainable and robust analytical approach.
Yukta Vijay Kotecha, Dinesh Dattatray Rishipathak, Rakesh Uttamrao Shelke, Vijay Arjun Bagul, Anand Radheshyam Tiwari, Suryakant D. Bhosle   +5 more
doaj   +1 more source

Quality by design- assisted green HPLC and UPLC methods: Advancing sustainable analytical chemistry for climate action - a review

Sustainable Chemistry for Climate Action
Integrating Green Analytical Chemistry (GAC) and Analytical Quality by Design (AQbD) is a milestone development which drives the direction of research towards inevitable paradigm shift of developing, designing, and running of analytical approaches. These
Sujith Kumar K, Kokilambigai K S, Seetharaman R   +2 more
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Analytical quality by design (AQbD) based optimization of RP-UPLC method for determination of nivolumab and relatlimab in bulk and pharmaceutical dosage forms

Future Journal of Pharmaceutical Sciences
Background The Analytical Quality by Design (AQbD) methodology extends the application of Quality by Design (QbD) principles to the management of the analytical procedure life cycle, encompassing method creation, optimization, validation, and continuous ...
Mohana Vamsi Nuli, Ramanjaneyulu Seemaladinne, Anil Kumar Tallam   +2 more
doaj   +1 more source

Central composite design (CCD) approach to develop HPLC method for caffeine: Application to coffee samples analysis of Jazan region, Saudi Arabia

Journal of Saudi Chemical Society
The goal of this study was to use High performance liquid chromatography (HPLC) with an Analytical Quality by Design (AQbD) approach to measure the amount of caffeine in selected coffee samples available in the local Jazan market in Saudi Arabia.
Asim Najmi, Zia ur Rehman, Khalid Zoghebi, Hassan Ahmed Alhazmi, Mohammed Mofarreh Albratty, Qasem Yahya Hassan Haroobi, Ismail Mohammed Ali Sayram, Mohammed Ahmed Saleh, Waleed Mohammed Ahmed Qaser, Abdulaziz Ali Houssein Qaysi   +9 more
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AQbD guided optimization and validation of RP-HPLC method for Vildagliptin

Vildagliptin is an anti-diabetic drug used primarily for type 2 diabetes mellitus. One of themain reasons quality is lost in pharmaceuticals is the absence of appropriate and valid analyticaltechniques. This paper aims to describe the development and verification of a Quality byDesign (QbD) RP-HPLC method to determine Vildagliptin in bulk and tablet ...
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The use of QbD for the development and validation of a stability-indicating RP-HPLC method for the quantitation of nevirapine in bulk, tablet and niosome formulations

Frontiers in Analytical Science
IntroductionA reversed-phase high-performance liquid chromatographic (RP-HPLC) method was developed and validated for the quantitation of nevirapine (NVP) in bulk drug, commercial tablets, and niosome formulations using an Analytical Quality by Design ...
Bwalya A. Witika, Roderick B. Walker
doaj   +1 more source

A REVIEW ON RECENT STRATEGIES IN AQbD APPROACH

Recent strategies in the Analytical Quality by Design (AQbD) approach have transformed the way analytical methods are developed, optimized, and controlled in pharmaceutical and regulatory environments. AQbD integrates scientific knowledge and risk-based strategies to ensure the consistent performance and quality of analytical methods throughout their ...
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Environmentally sustainable analytical quality by design aided RP-HPLC method for the estimation of brilliant blue in commercial food samples employing a green-ultrasound-assisted extraction technique

Green Processing and Synthesis, 2023
Chakraborty Atyurmila, Jayaseelan Kavitha   +1 more
doaj   +1 more source

Analytical Quality by Design (AQbD) for Quality and Risk Assessment of Pharmaceuticals to Immunomarkers

Journal of Pharmaceutical and Biopharmaceutical Research
Using advanced scientific and risk-based approaches for analytical methods offers significant benefits. Quality by Design (QbD) is a systematic framework that emphasizes understanding and controlling both product and process elements. Adhering to the principles outlined in the ICH guidelines can considerably improve the quality of drug substances ...
Vivekanandan Kalaiselvan, Meenakshi Dahiya, Gaurav Sanjay Mahalpure, Ritu Tiwari   +3 more
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A Mini Overview of Analytical Quality by Design (AQbD)

A methodical, science- and risk-based approach to pharmaceutical development, Quality by  Design (QbD) emphasizes incorporating quality into goods rather than depending just on end product testing. Through standards like ICH Q8 (Pharmaceutical Development), Q9 (Quality Risk  Management), and Q10 (Pharmaceutical Quality System), regulatory bodies ...
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