Results 31 to 40 of about 796 (185)
Journal of Chemical Technology &Biotechnology, Volume 97, Issue 9, Page 2347-2364, September 2022., 2022 Abstract The transition to continuous biomanufacturing is considered the next step to reduce costs and improve process robustness in the biopharmaceutical industry, while also improving productivity and product quality. The platform production process for monoclonal antibodies (mAbs) is eligible for continuous processing to lower manufacturing costs ...
Mariana N São Pedro +3 more
wiley +1 more source
Sixteen capillary electrophoresis applications for viral vaccine analysis
ELECTROPHORESIS, Volume 43, Issue 9-10, Page 1068-1090, May 2022., 2022 Abstract A broad range of CE applications from our organization is reviewed to give a flavor of the use of CE within the field of vaccine analyses. Applicability of CE for viral vaccine characterization, and release and stability testing of seasonal influenza virosomal vaccines, universal subunit influenza vaccines, Sabin inactivated polio vaccines ...
Lars Geurink +6 more
wiley +1 more source
International Journal of Analytical Chemistry, Volume 2022, Issue 1, 2022., 2022 Quality‐by‐design (QbD) is defined as a systematic approach to design and develop a product/service based on sound science and quality risk management. It is already frequently applied in the pharmaceutical industry mainly in the development of pharmaceutical products and analytical methods but is not well established in the setup of facilities like ...
Sultan Suleman +9 more
wiley +1 more source
Green RP-UPLC Method for Simultaneous Determination of Cyclopentolate and Organic Impurities Using DoE and Sustainability Metrics. [PDF]
Int J Anal ChemA significant improvement in sustainability and efficiency is achievable through green and white chemistry. As part of this study, sustainability assessment tools were used to assess the environmental impact and practicality of an innovative, straightforward RP‐UPLC method to analyze cyclopentolate (CLO) and its organic impurities simultaneously in ...
Alsehli BR +5 more
europepmc +2 more sources
Analytical Science Advances, Volume 2, Issue 1-2, Page 2-14, February 2021., 2021 Abstract The aim of this work was to develop a supercritical fluid chromatographic method to study the applicability of this emerging technique to cannabinoid analysis and showcase its advantages. During method development, the authors focused on nine phyto‐cannabinoids to assess the selectivity needed to potentially perform the quantitation of each ...
Riccardo Deidda +7 more
wiley +1 more source
ELECTROPHORESIS, Volume 42, Issue 1-2, Page 10-18, January 2021., 2021 Abstract Vaccines against infectious diseases are urgently needed. Therefore, modern analytical method development should be as efficient as possible to speed up vaccine development. The objectives of the study were to identify critical method parameters (CMPs) and to establish a set of steps to efficiently develop and validate a CE‐SDS method for ...
Lars Geurink +4 more
wiley +1 more source
Molecules, 2021 A novel and efficient stability-indicating, reverse phase ultra-performance liquid chromatographic (UPLC®) analytical method was developed and validated for the determination of hexoprenaline in an injectable dosage form.
Jesús Alberto Afonso Urich +5 more
doaj +1 more source
Application of AQbD to cIEF of Protein Biopharmaceuticals [PDF]
Biomedical Journal of Scientific & Technical Research, 2019 Protein biopharmaceuticals like monoclonal antibodies (mAbs), recombinant and therapeutic proteins are recently in widespread treated of various diseases including cancer, autoimmune disease, cardiovascular, hematology and so on...
openaire +1 more source
Vector control method applied to a traveling wave in a finite beam [PDF]
, 2014 This paper presents the closed-loop control of exciters to produce a traveling wave in a finite beam. This control is based on a dynamical modeling of the system established in a rotating reference frame.
AMBERG, Michel +3 more
core +6 more sources
Method operable design region obtained with a partial least squares model inversion in the determination of ten polycyclic aromatic hydrocarbons by liquid chromatography with fluorescence detection [PDF]
, 2021 A chromatographic method with the Analytical Quality by Design (AQbD) methodology is developed for the simultaneous determination by HPLC-FLD of ten PAHs (naphthalene, phenanthrene, anthracene, flu- oranthene, pyrene, chrysene, benzo[a]anthracene ...
Arce Antón, Mar +5 more
core +1 more source