Results 121 to 130 of about 1,373 (155)
Aquaglyceroporins and orthodox aquaporins in human adipocytes
Biochimica Et Biophysica Acta - Biomembranes, 2022 Aquaporins play a crucial role in water homeostasis in the human body, and recently the physiological importance of aquaporins as glycerol channels have been demonstrated. The aquaglyceroporins (AQP3, AQP7, AQP9 and AQP10) represent key glycerol channels, enabling glycerol flux across the membranes of cells.
Florentina Negoita +2 more
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Aquaglyceroporins: Generalized metalloid channels [PDF]
Biochimica Et Biophysica Acta - General Subjects, 2014 Aquaporins (AQPs), members of a superfamily of transmembrane channel proteins, are ubiquitous in all domains of life. They fall into a number of branches that can be functionally categorized into two major sub-groups: i) orthodox aquaporins, which are water-specific channels, and ii) aquaglyceroporins, which allow the transport of water, non-polar ...
Barry P Rosen +2 more
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Aquaglyceroporins: ancient channels for metalloids [PDF]
Journal of Biology, 2008 The identification of aquaglyceroporins as uptake channels for arsenic and antimony shows how these toxic elements can enter the food chain, and suggests that food plants could be genetically modified to exclude arsenic while still accumulating boron and silicon.
Barry P Rosen +2 more
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A Current View of the Mammalian Aquaglyceroporins
Annual Review of Physiology, 2008The discovery of aquaporin water channels by Agre and coworkers answered a long-standing biophysical question of how the majority of water crosses biological membranes. The identification and study of aquaporins have provided insight, at the molecular level, into the fundamental physiology of water balance regulation and the pathophysiology of water ...
Jeppe Praetorius +2 more
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Involvement of aquaglyceroporins in energy metabolism in health and disease [PDF]
Biochimie, 2021 Aquaglyceroporins are a group of the aquaporin (AQP) family of transmembrane water channels. While AQPs facilitate the passage of water, small solutes, and gases across biological membranes, aquaglyceroporins allow passage of water, glycerol, urea and some other solutes.
Christine Delporte, Giuseppe Calamita
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Adaptive Selection in the Evolution of Aquaglyceroporins in Mammals
Journal of Molecular Evolution, 2023Aquaporins (AQPs) are integral membrane proteins responsible for water transport across cellular membranes in both prokaryotes and eukaryotes. A subfamily of AQPs, known as aquaglyceroporins (AQGPs), facilitate the transport of small solutes such as glycerol, water, and other solutes across cellular membranes.
De S, De Sachinandan
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Mechanism of selectivity in aquaporins and aquaglyceroporins [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2008 Aquaporins and aquaglyceroporins form a family of pore proteins that facilitate the efficient and selective flux of small solutes across biological membranes. We studied the selectivity of aquaporin-1 (AQP1) and the bacterial glycerol facilitator, GlpF, for O 2 , CO 2
Jochen Hub +2 more
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Aquaglyceroporins, one channel for two molecules
Biochimica Et Biophysica Acta - Bioenergetics, 2002 In the light of the recently published structure of GlpF and AQP1, we have analysed the nature of the residues which could be involved in the formation of the selectivity filter of aquaporins, glycerol facilitators and aquaglyceroporins. We demonstrate that the functional specificity for major intrinsic protein (MIP) channels can be explained on one ...
Celine Raguenes-Nicol +2 more
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Aquaglyceroporins: implications in adipose biology and obesity
Cellular and Molecular Life Sciences, 2014Aquaporins (AQPs) are membrane water/glycerol channels that are involved in many physiological processes. Their primary function is to facilitate the bidirectional transfer of water and small solutes across biological membranes in response to osmotic gradients.
Graça Soveral +2 more
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