Results 201 to 210 of about 24,621,355 (297)

Olive Leaf Extract (OLE) impaired vasopressin-induced aquaporin-2 trafficking through the activation of the calcium-sensing receptor. [PDF]

Sci Rep, 2021
Ranieri M, Di Mise A, Centrone M, D'Agostino M, Tingskov SJ, Venneri M, Pellegrino T, Difonzo G, Caponio F, Norregaard R, Valenti G, Tamma G.   +11 more
europepmc   +1 more source

Ion Channel Dysfunction and Therapeutic Targeting in Salivary Gland Disorders

Oral Diseases, EarlyView.
ABSTRACT Objective Salivary gland hypofunction and xerostomia represent major clinical complications of radiation therapy, autoimmune disorders such as Sjögren's disease, and inherited epithelial ion transport defects. This review integrates current knowledge on ion channel dysfunction as a central mechanistic driver of salivary gland pathology and ...
Tarek Mohamed Abd El‐Aziz, Shankara N. Varadarajan, Viktor Drel, Prakash Arullampalam, Mahmoud I. Shoulkamy, Ahmed Al‐Sabi, Brij B. Singh   +6 more
wiley   +1 more source

Disruption of mitochondrial electron transport impairs urinary concentration via AMPK-dependent suppression of aquaporin 2. [PDF]

JCI Insight
Carty JS, Bessho R, Zuchowski Y, Trapani JB, Davidoff O, Kobayashi H, Roland JT, Watts JA, Terker AS, Bock F, Arroyo JP, Haase VH.   +11 more
europepmc   +1 more source

Converging GWAS and Genome Editing Decrypts MsCBF8‐MsGolS2 Regulatory Module for Drought Tolerance Without Yield Penalty in Medicago sativa

Plant Biotechnology Journal, EarlyView.
ABSTRACT Drought constitutes a major abiotic stress limiting alfalfa productivity. To elucidate the genetic basis of drought tolerance, a genome‐wide association study (GWAS) was conducted in alfalfa, which identified a CBF/DREB1 family transcription factor designated MsCBF8.
Yangyang Zhang, Xueqian Jiang, Tian Zhang, Huajuan Leng, Jing Cui, Xu Jiang, Lili Zhang, Zhen Wang, Tiejun Zhang, Qingchuan Yang, Xue Wang, Junmei Kang   +11 more
wiley   +1 more source

Tolvaptan and the role of kidney aquaporin-2 abundance in managing volume overload in patients with CKD. [PDF]

Clin Kidney J
Yan Y, Li XM, Yang Y, Wang FM, Liu H, Tang RN, Zhang XL, Liu BC, Wang B.   +8 more
europepmc   +1 more source

Deciphering Role of Endophytes in Plant Defences and Biotic Stress Resilience Across Families

Plant, Cell &Environment, EarlyView.
ABSTRACT Plant families generate distinct repertoires of specialised metabolites that govern their biotic interactions. Endophytes strengthen host plant defence mechanisms and tolerance to biotic challenges by upregulating metabolite biosynthesis, modifying precursor compounds into more potent forms, or by directly synthesising analogous defence ...
S. Aneeqa Noor, Kavita Verma, Nishu, Barkat Hussain, Vartika Mathur   +4 more
wiley   +1 more source

Molecular Chaperone Networks in Plants: Maintaining Proteostasis and Enhancing Stress Resilience for Crop Improvement

Plant, Cell &Environment, EarlyView.
ABSTRACT Molecular chaperones play a central role in the plant proteostasis machinery by aiding the folding of nascent proteins, preventing aggregation, and repairing or degrading damaged proteins. These functions are especially essential during abiotic and biotic stress, which can destabilise cellular proteins and disrupt metabolic homoeostasis.
Mingfang Yang, Anqin Gao, Tsz‐Yan Chan, Hafiz Mamoon Rehman, Sehar Nawaz, Sehrish Bashir, Noman Mahmood, Muhammad Wajid Ullah, Chunlin Long, Hon‐Ming Lam, Muhammad Arif   +10 more
wiley   +1 more source

Goreisan promotes diuresis by regulating the abundance of aquaporin 2 phosphorylated at serine 269 through calcium-sensing receptor activation. [PDF]

Sci Rep
Ogura K, Fujitsuka N, Nahata M, Tokita Y.   +3 more
europepmc   +1 more source

Unravelling the Intraspecific Variation in Drought Responses in Seedlings of European Black Pine (Pinus Nigra J.F. Arnold)

Plant, Cell &Environment, EarlyView.
ABSTRACT Understanding intraspecific variation in drought tolerance is essential for predicting the adaptive capacity of forest species under climate change. Yet, the molecular basis of this variation remains poorly understood in ecologically and economically important conifers.
Muhammad Ahmad, Almuth Hammerbacher, Clara Priemer, Albert Ciceu, Marta Karolak, Sonja Mader, Sanna Olsson, Johann Schinnerl, Sebastian Seitner, Selina Schöndorfer, Paula Helfenbein, Jakub Jez, Michaela Breuer, Ana Espinosa‐Ruiz, Teresa Caballero, Andrea Ganthaler, Stefan Mayr, Dominik K. Großkinsky, Stefanie Wienkoop, Silvio Schueler, Carlos Trujillo‐Moya, Marcela van Loo   +21 more
wiley   +1 more source

Integrated Analysis of Grapevine Responses to Winter Pruning Reveals Temperature‐Associated, Polyphenol‐Rich Xylem Occlusions

Plant, Cell &Environment, EarlyView.
ABSTRACT Perennial crops are continually wounded throughout cultivation. To limit pathogen infection and tissue dehydration, plants have evolved a range of wound responses that protect damaged tissues. These responses include changes in gene expression and the synthesis of protective compounds such as polyphenols.
Marilou Camboué, Monica Galar‐Martínez, Grégoire Loupit, Paraskevi Charalambous, Enric Zehraoui, Joseph Tran, Josep Valls Fonayet, Luis Gonzaga Santesteban, Notburga Gierlinger, Sarah Jane Cookson   +9 more
wiley   +1 more source