Results 201 to 210 of about 38,256 (256)

Chronic Smoking Impairs Glymphatic Transport and Cognitive Function in Adolescent Mice Through Cardiac, Vascular, and Perivascular Aquaporin‐4 Mechanisms

CNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.
Chronic smoking during adolescence impairs glymphatic transport, leading to cognitive decline and aberrant accumulation of phosphorylated tau in the hippocampal DG region. Smoking‐induced glymphatic dysfunction compromises synaptogenesis and neurogenesis in the hippocampal DG region.
Chuanxiang Lv, Chengyu Xia, Zean Li, Tao Liu, Zhuang Sha, Shiying Dong, Yu Qian, Mingqi Liu, Kang Zhang, Xinran Zhang, Rongcai Jiang, Li Bie   +11 more
wiley   +1 more source

A bell-shaped pattern of urinary aquaporin-2-bearing extracellular vesicle release in an experimental model of nephronophthisis. [PDF]

Physiol Rep, 2019
Mikoda N, Sonoda H, Oshikawa S, Hoshino Y, Matsuzaki T, Ikeda M.   +5 more
europepmc   +1 more source

Altered Glymphatic‐Related MRI Metrics and Brain Network Reorganization in Drug‐Naive Children With Self‐Limited Epilepsy With Centrotemporal Spikes

CNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.
Drug‐naive children with SeLECTS exhibit altered glymphatic‐related MRI metrics, including reduced gBOLD‐CSF coupling and increased FW‐WM, together with disrupted functional network topology. The gBOLD‐CSF coupling is associated with nodal properties in key regions and with cognitive performance. These findings suggest that impaired brain clearance and
Yu Luo, Xiaoling Zhou, Jiajia Xu, Hua Lai, Qiang Lei, Yuwei Chen, Heng Liu   +6 more
wiley   +1 more source

Open‐Label, Balanced, Randomized, Single‐Dose, Three‐Treatment, Three‐Sequence, Three‐Period, Three‐Way Crossover Oral Bioequivalence Study of Desmopressin Acetate Oral Solution

Clinical Pharmacology in Drug Development, Volume 15, Issue 8, August 2026.
ABSTRACT Desmopressin is first‐line therapy for central diabetes insipidus, also known as arginine vasopressin deficiency, but presents dosing challenges due to its narrow therapeutic index. This open‐label, randomized, three‐way crossover study evaluated the bioequivalence of a new desmopressin acetate oral solution (50 mcg/mL) compared to ...
Adam Christensen, Axay Parth, Mansi Kotak, Danka Radosavjevic, Catherine Gorman Moore, Byung‐Woun Seo   +5 more
wiley   +1 more source

From scarring to healing: Emerging regenerative therapies for pulmonary fibrosis using MSCs and exosomes

Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.
MSCs exert anti‐inflammatory, anti‐fibrotic and regenerative effects in pulmonary fibrosis. MSC‐derived exosomes reproduce many therapeutic benefits of parental MSCs. Preconditioning and genetic modification improve MSC therapeutic performance. Current preclinical and clinical evidence supports the translational potential of MSC‐based therapies ...
Hajar Nasiri, Farbod Khosravi, Fatemeh Eskandari, Tahereh Manoochehrabadi, Ali Samadikuchaksaraei, Ehsan Lotfi, Jila Majidi, Fatemeh Rafati, Zeynab Ghorbani   +8 more
wiley   +1 more source

Expert Treatment Considerations for Lower Face and Neck Rejuvenation

Dermatological Reviews, Volume 7, Issue 4, August 2026.
ABSTRACT Background The lower face and neck are essential to overall facial harmony and a balanced appearance. Although most nonsurgical treatments have focused on the upper and midface, a variety of minimally invasive options are now available for treating the lower face and neck that target different aesthetic concerns and provide welcome ...
Sabrina Fabi, John Fezza, Jeremy B. Green, Jean Carruthers, Nazanin Ashourian, Elena Dimitrijevic, Steven Yoelin   +6 more
wiley   +1 more source

Enhancement of Morpho‐Physiological, Physiological, and Antioxidant Capacity of Saffron (Crocus sativus L.) Under Water Deficit Using ZnO Nanoparticles and Magnesium Sulfate: Implications for Saffron Yield

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
ZnO nanoparticles and MgSO4 synergistically alleviated drought‐induced damage in saffron. Foliar application improved relative water content and antioxidant enzyme activity. Photosynthetic performance and membrane stability were enhanced under water deficit. Moderate drought combined with ZnO‐NPs and MgSO4 maximized saffron productivity. ABSTRACT Water
Laila Turki, Seham Zaben, Ekhlas Meteab Ahmed Marir, Heidar Meftahizade   +3 more
wiley   +1 more source

Yin Yang 1 Specifically Supports the Development of Olig2 Positive Cerebellar Astrocytes

Glia, Volume 74, Issue 8, August 2026.
Cerebellar Olig2 positive astrocytes are most abundant in the cerebellar nuclei. Cerebellar astrocytes expressing Olig2 have unique gene expression profiles. Yin Yang 1 specifically supports the development of astrocytes expressing Olig2. Deletion of YY1 during development increases numbers of astrocytes expressing Olig2 but hinders their ...
Masoumeh Zarei‐Kheirabadi, Katarzyna M. Tyc, Lauren Dain, Maryam Ashrafi Kheirabadi, Jennifer Hanco, Karli Mockenhaupt, Soha Munir, Adam McQuiston, Sandeep K. Singh, Tomasz Kordula   +9 more
wiley   +1 more source

Clinical Significance and Changes in Levels of Serum BDNF, mBDNF, AQP4, proBDNF, and GSK3β in Individuals Diagnosed With Bipolar Disorder: A Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Bipolar disorder (BD) is a severe mood disorder with unclear pathogenesis and limited diagnostic biomarkers. This study aimed to evaluate serum levels of BDNF, mBDNF, AQP4, proBDNF, and GSK3β between BD patients and healthy controls, and to preliminarily explore their potential clinical significance.
Jiawei Zhou, Chunying Zhu, Juezhuo Li, Lailing Du, Jinghua Yuan, Kewei Tian, Xinling Zhang, Xiaoping Li   +7 more
wiley   +1 more source

Trends in Clinical Indications for Plasma Exchange in Adult Patients Between 2008 and 2024 in Bogotá, Colombia

Journal of Clinical Apheresis, Volume 41, Issue 4, August 2026.
ABSTRACT This multicenter retrospective study aimed to describe temporal trends in clinical indications for plasma exchange (PE) in adult patients at four quaternary‐care hospitals in Bogotá (2008–2024) and to examine their distribution across successive ASFA guideline editions.
Edgar Julián Reyes, Federico Tovar‐Avendaño, Camilo Alberto Gonzalez‐Gonzalez, Diana Carolina Vargas‐Angel, Jorge Pulido, Paula Violeta Rodríguez, Deiner‐Yivelson Muñoz‐Delgado, Kateir Contreras‐Villamizar   +7 more
wiley   +1 more source