Results 31 to 40 of about 33,882 (227)

Altered aquaporin 9 expression and localization in human hepatocellular carcinoma [PDF]

HPB, 2009
In addition to the biochemical components secreted in bile, aquaporin (AQP) water channels exist in hepatocyte membranes to form conduits for water movement between the sinusoid and the bile canaliculus. The aim of the current study was to analyse AQP 9 expression and localization in human hepatocellular carcinoma (HCC) and non-tumourigenic liver (NTL)
Padma, Srikanth, Smeltz, Alan M., Banks, Peter M., Iannitti, David A., McKillop, Iain H.   +4 more
openaire   +2 more sources

Aquaporin‐9 expression in malignant glioma

The FASEB Journal, 2011
Recent studies described enhanced expression of the water channel aquaporin 9 (AQP9) in biopsies of glioblastoma patients. This may indicate a function for AQP9 in glioma progression as water channels are known to contribute to cell migration. Furthermore, AQP9 is a glycerol and lactate channel and could play a role in the energy metabolism of ...
Sabina Katarzyna Jelen, Michael Rützler
openaire   +1 more source

Defective glycerol metabolism in aquaporin 9 (AQP9) knockout mice [PDF]

Proceedings of the National Academy of Sciences, 2007
Aquaporin-9 (AQP9) is an aquaglyceroporin membrane channel shown biophysically to conduct water, glycerol, and other small solutes. Because the physiological role/s of AQP9 remain undefined and the expression sites of AQP9 remain incomplete and conflicting, we generated AQP9 knockout mice.
Nielsen, S, Frøkiær, Jørgen, Agre, Peter, Fenton, R. A., Füchtbauer, A C, Furman, C. Sue, Skowronski, M. T., Rojek, A M   +7 more
openaire   +2 more sources

Effectiveness of porous silicon nanoparticle treatment at inhibiting the migration of a heterogeneous glioma cell population

Journal of Nanobiotechnology, 2021
Background Approximately 80% of brain tumours are gliomas. Despite treatment, patient mortality remains high due to local metastasis and relapse. It has been shown that transferrin-functionalised porous silicon nanoparticles (Tf@pSiNPs) can inhibit the ...
Youssef Abdalla, Meihua Luo, Ermei Mäkilä, Bryan W. Day, Nicolas H. Voelcker, Wing Yin Tong   +5 more
doaj   +1 more source

Aquaporin 9 phosphorylation mediates membrane localization and neutrophil polarization [PDF]

Journal of Leukocyte Biology, 2011
ABSTRACTNeutrophils are of prime importance in the host innate defense against invading microorganisms by using two primary mechanisms—locomotion toward and phagocytosis of the prey. Recent research points to pivotal roles for water channels known as AQPs in cell motility. Here, we focused on the role of AQP9 in chemoattractant-induced polarization and
Thommie, Karlsson, Michael, Glogauer, Richard P, Ellen, Vesa-Matti, Loitto, Karl-Eric, Magnusson, Marco A O, Magalhães   +5 more
openaire   +2 more sources

Fluxes of water through aquaporin 9 weaken membrane-cytoskeleton anchorage and promote formation of membrane protrusions. [PDF]

PLoS ONE, 2013
All modes of cell migration require rapid rearrangements of cell shape, allowing the cell to navigate within narrow spaces in an extracellular matrix.
Thommie Karlsson, Anastasia Bolshakova, Marco A O Magalhães, Vesa M Loitto, Karl-Eric Magnusson   +4 more
doaj   +1 more source

Immunolocalization of Aquaporin-9 in Rat Hepatocytes and Leydig Cells.

Archives of Histology and Cytology, 2001
The aquaporin (AQP)-9 gene was recently isolated from human and rat liver cDNA libraries as a member of the water channel family for water and neutral solutes. Although the expression of AQP9 mRNA has been demonstrated in several organs including the liver and testis by Northern blot analysis, the cellular and subcellular localization of the AQP9 ...
NIHEI, Kouei, KOYAMA, Yu, TANI, Tatsuo, YAOITA, Eishin, OHSHIRO, Kazufumi, ADHIKARY, Laxman P., KUROSAKI, Isao, SHIRAI, Yoshio, HATAKEYAMA, Katsuyoshi, YAMAMOTO, Tadashi   +9 more
openaire   +3 more sources

Effects of acupuncture at GV20 and ST36 on the expression of matrix metalloproteinase 2, aquaporin 4, and aquaporin 9 in rats subjected to cerebral ischemia/reperfusion injury. [PDF]

PLoS ONE, 2014
BACKGROUND/PURPOSE: Ischemic stroke is characterized by high morbidity and mortality worldwide. Matrix metalloproteinase 2 (MMP2), aquaporin (AQP) 4, and AQP9 are linked to permeabilization of the blood-brain barrier (BBB) in cerebral ischemia ...
Hong Xu, Yamin Zhang, Hua Sun, Suhui Chen, Fuming Wang   +4 more
doaj   +1 more source

Blue Light Induces Down-Regulation of Aquaporin 1, 3, and 9 in Human Keratinocytes

Cells, 2018
The development in digital screen technology has exponentially increased in the last decades, and many of today’s electronic devices use light-emitting diode (LED) technology producing very strong blue light (BL) waves. Long-term exposure at LED-BL
Rosanna Avola, Adriana Carol Eleonora Graziano, Giovanna Pannuzzo, Venera Cardile   +3 more
doaj   +1 more source

Association of Serum Dystroglycan, MMP-2/9 and AQP-4 with Haematoma Expansion in Patients with Intracerebral Haemorrhage

Neuropsychiatric Disease and Treatment, 2021
Yue Shi,1 Xuehui Fan,1 Guozhong Li,1 Di Zhong,1 Xin Zhang2 1Department of Neurology, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, Heilongjiang Province, People’s Republic of China; 2Department of Neurology, Liuzhou ...
Shi Y, Fan X, Li G, Zhong D, Zhang X
doaj