Results 111 to 120 of about 75,608 (261)

TRPV4 Contributes to Resting Membrane Potential in Retinal Müller Cells: Implications in Cell Volume Regulation [PDF]

, 2017
Neural activity alters osmotic gradients favoring cell swelling in retinal Müller cells. This swelling is followed by a regulatory volume decrease (RVD), partially mediated by an efflux of KCl and water. The transient receptor potential channel 4 (TRPV4),
Capurro, Claudia Graciela, Di Giusto, Gisela, Fernández, Juan, Ford, Paula, Kalstein, Maia, Netti, Vanina Alejandra, Pizzoni, Alejandro, Rivarola, Valeria   +7 more
core   +1 more source

Differential glymphatic dysfunction and memory correlation in temporal lobe epilepsy subtypes

Epilepsia Open, EarlyView.
Abstract Objective This study aims to evaluate the glymphatic system (GS) in different temporal lobe epilepsy (TLE) subtypes using diffusion tensor imaging analysis along the perivascular space (DTI‐ALPS) and to explore its correlation with clinical factors and memory performance.
Ruotong Chen, Hong Li, Pu Miao, Hongyi Ye, Xiao Chen, Yuyu Yang, Jinqi Zhou, Yihe Chen, Yi Ge, Chenmin He, Xiaotong Shao, Zijian Wang, Yuting Gong, Cong Chen, Shan Wang, Lingli Hu, Lingqi Ye, Yao Ding, Shuang Wang, Linglin Yang   +19 more
wiley   +1 more source

Sojae Semen Praeparatum Fermented by Rhizopus chinensis and Bacillus sp. DU‐106 Alleviates Loperamide‐Induced Constipation in Rats via Regulating Calcium Signaling Pathways and the Gut Microbiota

Food Frontiers, EarlyView.
To investigate the effects of different processing methods of Sojae Semen Praeparartum (SSP) on constipation, we prepared SSP through fermentation using Rhizopus chinensis and Bacillus sp. DU‐106 as starter cultures, and examined its laxative effects and mechanisms in loperamide‐induced constipated Sprague‐Dawley (SD) rats.
Rong xiang Guo, Chao fan Zhao, Yan li Li, Yun xi Zhang, Fu Yao Luo, Yi hang Sun, Ya fei Wang, Jun Yuan Huang, Bing Du, Pan Li   +9 more
wiley   +1 more source

Aquaporin Protein-Protein Interactions

International Journal of Molecular Sciences, 2017
Aquaporins are tetrameric membrane-bound channels that facilitate transport of water and other small solutes across cell membranes. In eukaryotes, they are frequently regulated by gating or trafficking, allowing for the cell to control membrane ...
J. Roche, S. Törnroth-Horsefield
semanticscholar   +1 more source

Neuronal THY1 Signaling Maintains Astrocytes in a Quiescent State

Glia, EarlyView.
THY1‐bearing neurons keep astrocytes in a quiescent state via the interaction with ITGB1. Depletion of THY1 supports the development of a partially activated astrocyte phenotype. Neuronal THY1 is involved in the maintenance and restoration of tissue homeostasis in the brain. ABSTRACT THY1 is a cell surface protein of mature neurons.
Juliane Loui, Ute Krügel, Ulrike Winkler, Anja Reinert, Dorit John, Johannes Hirrlinger, Anja Saalbach   +6 more
wiley   +1 more source

Pancreatic Aquaporin-7: A Novel Target for Anti-diabetic Drugs?

Frontiers in Chemistry, 2018
Aquaporins comprise a family of 13 members of water channels (AQP0-12) that facilitate a rapid transport of water across cell membranes. In some cases, these pores are also permeated by small solutes, particularly glycerol, urea or nitric oxide, among ...
Leire Méndez-Giménez, Leire Méndez-Giménez, Silvia Ezquerro, Silvia Ezquerro, Inês V. da Silva, Graça Soveral, Gema Frühbeck, Gema Frühbeck, Gema Frühbeck, Amaia Rodríguez, Amaia Rodríguez   +10 more
doaj   +1 more source

The Impact of Aquaporin‐4 Deletion on K+‐Induced Astrocytic Swelling Depends on K+ Concentration

Glia, EarlyView.
Swelling due to 10 mM [K+]o is reduced in astrocytes devoid of aquaporin‐4, while there is no difference between genotypes when exposed to 50 mM [K+]o. The two [K+]o concentrations induce distinct astrocytic Ca2+ signaling in the two genotypes pointing to a possible mechanistic basis of the differences observed. ABSTRACT Astrocytes swell in response to
Cecilie Bugge Bakketun, Lena Catherine Roth, Daniel Marelius Bjørnstad, Ole Petter Ottersen, Vidar Jensen, Rune Enger   +5 more
wiley   +1 more source

A case report: Diagnosis and treatment of idiopathic hypertrophic pachymeningitis

Ibrain, Volume 11, Issue 1, Page 112-116, Spring 2025.
We reported a case of idiopathic hypertrophic dura meningitis diagnosed in our hospital. The patient repeatedly suffered from headaches, followed by blurred vision in the right eye. During this period, multiple sclerosis was considered for diagnosis, and it improved after hormone treatment.
Zhong Luo, Piao Cao, Jing‐Qing Xu, Rong Yan, Jian Wang, Tao Liang, Ya Chen, Zu‐Cai Xu   +7 more
wiley   +1 more source

Research progress of neurovascular units involved in ischemic stroke

Ibrain, EarlyView.
The brain receives less blood when an ischemic stroke develops, which damages neurons and leads to an increased release of Pro‐inflammatory mediators that activate neurovascular unit (NVU). When the tight junctions are broken and the basement membrane is disrupted by matrix metalloproteinases produced by active endothelial and pericellular cells ...
Yu Yang, Hao Tong, Zhuo‐Fan Ye, Zu‐Cai Xu, Tao Tao   +4 more
wiley   +1 more source

Roles of Plasmalemma Aquaporin Gene StPIP1 in Enhancing Drought Tolerance in Potato

Frontiers in Plant Science, 2017
Survival and mortality of plants in response to severe drought may be related to carbon starvation, but little is known about how plasma membrane intrinsic proteins may help alleviate the drought-induced damage.
Junlian Zhang, Junlian Zhang, Li Wang, Li Wang, Yuhui Liu, Shoujiang Feng, Jiangwei Yang, Jiangwei Yang, Dan Li   +8 more
doaj   +1 more source