Results 91 to 100 of about 64,606 (299)

The inositol Inpp5k 5-phosphatase affects osmoregulation through the vasopressin-aquaporin 2 pathway in the collecting system [PDF]

, 2018
Inositol Inpp5k (or Pps, SKIP) is a member of the inositol polyphosphate 5-phosphatases family with a poorly characterized function in vivo. In this study, we explored the function of this inositol 5-phosphatase in mice and cells overexpressing the 42 ...
Beauwens, Renaud, Blockmans, Marianne, Cheong, Siew, Devuyst, Olivier, Erneux, Christophe, Gayral, Stéphanie, Jacoby, Monique, Janas, Sylvie, Markadieu, Nicolas, Pernot, Eileen, Pouillon, Valérie, Rossier, Bernard, Schurmans, Stéphane, Terryn, Sara   +13 more
core  

Amelioration of Post‐Stroke Edema and Microcirculatory Dysfunction via Targeted AQP4 Inhibition While Preserving the Glymphatic System

Advanced Science, EarlyView.
Compared to untargeted therapy, the targeted nanocarrier, Angiopep‐2‐conjugated Lipid Nanoparticle (A‐LNP) loaded with TGN‐020 (TGN), selectively accumulated in stroke‐injured regions. It suppressed local aquaporin‐4 (AQP4) overexpression, thereby alleviating cerebral edema and hypoperfusion while preserving global glymphatic clearance.
Lei Jin, Zeyu Yang, Boyang Wei, Yu Wu, Longxiang Li, Jiaming Zhou, Xin Zhang, Fa Jin, Shixing Su, Yanchao Liu, Ran Li, Shenquan Guo, Xingwu Liu, Yu Cai, Hong Liu, Min Chen, Wenchao Liu, Chuanzhi Duan, Xifeng Li   +18 more
wiley   +1 more source

Gi Protein Modulation of the Potassium Channel TASK-2 Mediates Vesicle Osmotic Swelling to Facilitate the Fusion of Aquaporin-2 Water Channel Containing Vesicles

Cells, 2018
Vesicle fusion is a fundamental cell biological process similar from yeasts to humans. For secretory vesicles, swelling is considered a step required for the expulsion of intravesicular content.
Mariangela Centrone, Maria Penelope De Santo, Isabella Nicotera, Cristina Labate, Marianna Ranieri, Annarita Di Mise, Maria Grazia Mola, Maria Mastrodonato, Rosangela Elliani, Riccardo Barberi, Vincenzo Formoso, Grazia Tamma, Giovanna Valenti   +12 more
doaj   +1 more source

Evaluation of four different strategies to characterize plasma membrane proteins from banana roots [PDF]

, 2015
Plasma membrane proteins constitute a very important class of proteins. They are involved in the transmission of external signals to the interior of the cell and selective transport of water, nutrients and ions across the plasma membrane.
Carpentier, Sebastien C., García, S., Panis, B., Swennen, Rony L.   +3 more
core   +1 more source

Aquaporin-2 water channels in spontaneously hypertensive rats [PDF]

American Journal of Hypertension, 2004
Vasopressin (AVP), an antidiuretic hormone, is known to induce hypervolemia and to regulate the renal expression of aquaporin-2 (AQP2) water channels, but it is not yet known whether the latter are involved in the pathogenesis of essential hypertension.
BUEMI, Michele, NOSTRO L, DI PASQUALE, Giuseppe, CAVALLARO, EMANUELA, STURIALE, ALESSIO, FLOCCARI F, ALOISI, Carmela, RUELLO A, CALAPAI, Gioacchino, CORICA, Francesco, FRISINA, Nicola   +10 more
openaire   +2 more sources

Myelitis‐Predominant Aggressive Phenotype: Unveiling Unique Patterns of Late‐Onset Neuromyelitis Optica Spectrum Disorders

Annals of Neurology, EarlyView.
Objective The objective of this study was to compare clinical features and prognosis of late‐onset neuromyelitis optica spectrum disorder (LO‐NMOSD, onset age ≥60 years) with adult‐onset NMOSD (AO‐NMOSD, onset age 18–59 years), and to provide insights for individualized management in elderly patients.
Ya‐Lan Pu, Jin‐Zhou Feng, Hua‐Xing Meng, Hai‐Bing Xiao, Xiao‐Ling Li, Jin Zhen, Wen‐Ying Lu, Xu‐Ming Xi, Ti Wu, Bao‐Shi Yuan, Mo‐Li Fan, Chao Zhang, De‐Cai Tian, Xia Meng, Fu‐Dong Shi, Tian Song   +15 more
wiley   +1 more source

In silico analysis of molecular mimicry between human aquaporin 3, Aspergillus fumigatus aquaporin and aquaporins from allergic sources [version 2; peer review: 2 approved]

F1000Research
Background Atopic dermatitis (AD) is a chronic inflammatory skin condition that has a significant impact on quality of life. The immune response and allergy symptoms in AD are triggered by the recognition of specific allergens by IgE antibodies.
Andrés Sánchez, Juan Urrego, Claudia Baena, Carlos Bernal, Adriana Lorduy, Jorge Sanchez, Marlon Munera, Yaquelin Padilla   +7 more
doaj   +1 more source

Comprehending the Membrane Properties for Emulation in Organs‐on‐a‐Chip

Advanced NanoBiomed Research, EarlyView.
The advent of organ‐on‐chip models allows closer emulation of in vivo conditions, leading to effective, less costly, and specific drugs. Although a number of membrane‐based on‐chip models exist, better emulating functional models need to be devised for organ simulations.
Tanmayee Makarand Sathe, Dhananjay Shrikrishna Bodas   +1 more
wiley   +1 more source

Visual Analytics for Robust Investigations of Placental Aquaporin Gene Expression in Response to Maternal SARS-CoV-2 Infection

Analytics
The human placenta is a multifunctional, disc-shaped temporary fetal organ that develops in the uterus during pregnancy, connecting the mother and the fetus.
Raphael D. Isokpehi, Amos O. Abioye, Rickeisha S. Hamilton, Jasmin C. Fryer, Antoinesha L. Hollman, Antoinette M. Destefano, Kehinde B. Ezekiel, Tyrese L. Taylor, Shawna F. Brooks, Matilda O. Johnson, Olubukola Smile, Shirma Ramroop-Butts, Angela U. Makolo, Albert G. Hayward   +13 more
doaj   +1 more source

The Aquaporin Channel Repertoire of the Tardigrade

Bioinformatics and Biology Insights, 2013
Limno-terrestrial tardigrades are small invertebrates that are subjected to periodic drought of their micro-environment. They have evolved to cope with these unfavorable conditions by anhydrobiosis, an ametabolic state of low cellular water.
Markus A. Grohme, Brahim Mali, Weronika Wełnicz, Stephanie Michel, Ralph O. Schill, Marcus Frohme   +5 more
doaj   +1 more source