Results 11 to 20 of about 64,606 (299)

Molecular Mechanisms and Drug Development in Aquaporin Water Channel Diseases: Water Channel Aquaporin-2 of Kidney Collecting Duct Cells

Journal of Pharmacological Sciences, 2004
Aquaporin-2 (AQP2) is one of the membrane water channel proteins expressed in principal cells of the kidney collecting ducts. In the basal state, AQP2 resides in the storage vesicles localized in the subapical cytoplasm. Upon stimulation with vasopressin,
Kuniaki Takata, Yuki Tajika, Toshiyuki Matsuzaki, Takeo Aoki, Takeshi Suzuki, Ablimit Abduxukur, Haruo Hagiwara   +6 more
doaj   +3 more sources

Vasopressin-Independent Regulation of Aquaporin-2 by Tamoxifen in Kidney Collecting Ducts. [PDF]

Front Physiol, 2019
Tingskov SJ, Choi HJ, Holst MR, Hu S, Li C, Wang W, Frøkiær J, Nejsum LN, Kwon TH, Nørregaard R.   +9 more
europepmc   +3 more sources

Shortening of primary cilia length is associated with urine concentration in the kidneys [PDF]

Kidney Research and Clinical Practice, 2023
Background The primary cilium, a microtubule-based cellular organelle present in certain kidney cells, functions as a mechano-sensor to monitor fluid flow in addition to various other biological functions.
Min Jung Kong, Sang Jun Han, Sung Young Seu, Ki-Hwan Han, Joshua H. Lipschutz, Kwon Moo Park   +5 more
doaj   +1 more source

MYC is a metastasis gene for non-small-cell lung cancer. [PDF]

, 2009
Metastasis is a process by which cancer cells learn to form satellite tumors in distant organs and represents the principle cause of death of patients with solid tumors. NSCLC is the most lethal human cancer due to its high rate of metastasis.
Castro, Inês, Ceteci, Fatih, Karreman, Christiaan, Korn, Christian, Luetkenhaus, Katharina, Potapenko, Tamara, Rapp, Ulf R., Serafin, Valentina, Zanucco, Emanuele   +8 more
core   +15 more sources

Effect of controlled hypotensive hemorrhage on plasma sodium levels in anesthetized pigs: An exploratory study

Physiological Reports, 2023
Perioperative hyponatremia, due to non‐osmotic release of the antidiuretic hormone arginine vasopressin, is a serious electrolyte disorder observed in connection with many types of surgery.
Rafael T. Krmar, Stephanie Franzén, Leif Karlsson, Helin Strandberg, Susanna Törnroth‐Horsefield, Jesper K. Andresen, Boye L. Jensen, Mattias Carlström, Robert Frithiof   +8 more
doaj   +1 more source

Minireview: Aquaporin 2 Trafficking [PDF]

Endocrinology, 2005
In the kidney aquaporin-2 (AQP2) provides a target for hormonal regulation of water transport by vasopressin. Short-term control of water permeability occurs via vesicular trafficking of AQP2 and long-term control through changes in the abundance of AQP2 and AQP3 water channels.
VALENTI, Giovanna, PROCINO, Giuseppe, TAMMA, GRAZIA, Carmosino M, SVELTO, Maria   +4 more
openaire   +3 more sources

'Aquaporin-omics': mechanisms of aquaporin-2 loss in polyuric disorders. [PDF]

J Physiol, 2023
AbstractAnimal models of a variety of acquired nephrogenic diabetes insipidus (NDI) disorders have identified a common feature: all such models are associated with the loss of aquaporin‐2 (AQP2) from collecting duct principal cells, explaining the associated polyuria.
Mak A, Sung CC, Pisitkun T, Khositseth S, Knepper MA.   +4 more
europepmc   +3 more sources

Evidence for a Prehypertensive Water Dysregulation Affecting the Development of Hypertension: Results of Very Early Treatment of Vasopressin V1 and V2 Antagonism in Spontaneously Hypertensive Rats

Frontiers in Cardiovascular Medicine, 2022
In addition to long-term regulation of blood pressure (BP), in the kidney resides the initial trigger for hypertension development due to an altered capacity to excrete sodium and water.
Ignazio Verzicco, Stefano Tedeschi, Gallia Graiani, Alice Bongrani, Maria Luisa Carnevali, Simona Dancelli, Jessica Zappa, Silvia Mattei, Achiropita Bovino, Stefania Cavazzini, Rossana Rocco, Anna Calvi, Barbara Palladini, Riccardo Volpi, Valentina Cannone, Pietro Coghi, Alberico Borghetti, Aderville Cabassi   +17 more
doaj   +1 more source

Expression of Aquaporin 2, Aquaporin 3 and Aquaporin 4 in Renal Medulla of Bactrian Camel ( Camelus bactrianus ) [PDF]

International Journal of Morphology, 2018
SUMMARY: Aquaporins (AQPs) are members of the aquaporin water channel family that play an important role in reabsorption of water from the renal tubular fluid to concentrate urine. Using immunohistochemical staining on paraffin sections, We studied expression of AQP2, AQP3 and AQP4 in renal medulla of Bactrian camel (Camelus bactrianus).
Jinbao Wang, Mengmeng Yang, Zhisheng Wang, Jing Wu, Jianmao Chen, Wen Yang, Jianlin Wang   +6 more
openalex   +3 more sources

AQP2 (aquaporin 2) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2019
Review on aquaporin-2 (AQP2), with data on DNA, on the protein encoded, and where the gene is implicated.
Jean‐Loup Huret
openalex   +3 more sources