Results 11 to 20 of about 36,467 (231)

Vasopressin-Independent Regulation of Aquaporin-2 by Tamoxifen in Kidney Collecting Ducts. [PDF]

Front Physiol, 2019
Tingskov SJ, Choi HJ, Holst MR, Hu S, Li C, Wang W, Frøkiær J, Nejsum LN, Kwon TH, Nørregaard R.   +9 more
europepmc   +3 more sources

Shortening of primary cilia length is associated with urine concentration in the kidneys [PDF]

Kidney Research and Clinical Practice, 2023
Background The primary cilium, a microtubule-based cellular organelle present in certain kidney cells, functions as a mechano-sensor to monitor fluid flow in addition to various other biological functions.
Min Jung Kong, Sang Jun Han, Sung Young Seu, Ki-Hwan Han, Joshua H. Lipschutz, Kwon Moo Park   +5 more
doaj   +1 more source

Effect of controlled hypotensive hemorrhage on plasma sodium levels in anesthetized pigs: An exploratory study

Physiological Reports, 2023
Perioperative hyponatremia, due to non‐osmotic release of the antidiuretic hormone arginine vasopressin, is a serious electrolyte disorder observed in connection with many types of surgery.
Rafael T. Krmar, Stephanie Franzén, Leif Karlsson, Helin Strandberg, Susanna Törnroth‐Horsefield, Jesper K. Andresen, Boye L. Jensen, Mattias Carlström, Robert Frithiof   +8 more
doaj   +1 more source

Evidence for a Prehypertensive Water Dysregulation Affecting the Development of Hypertension: Results of Very Early Treatment of Vasopressin V1 and V2 Antagonism in Spontaneously Hypertensive Rats

Frontiers in Cardiovascular Medicine, 2022
In addition to long-term regulation of blood pressure (BP), in the kidney resides the initial trigger for hypertension development due to an altered capacity to excrete sodium and water.
Ignazio Verzicco, Stefano Tedeschi, Gallia Graiani, Alice Bongrani, Maria Luisa Carnevali, Simona Dancelli, Jessica Zappa, Silvia Mattei, Achiropita Bovino, Stefania Cavazzini, Rossana Rocco, Anna Calvi, Barbara Palladini, Riccardo Volpi, Valentina Cannone, Pietro Coghi, Alberico Borghetti, Aderville Cabassi   +17 more
doaj   +1 more source

Aquaporin-10 represents an alternative pathway for glycerol efflux from human adipocytes. [PDF]

PLoS ONE, 2013
BACKGROUND: Glycerol outflow from adipocytes has been considered for a decade to be mediated by aquaporin-7, an aquaglyceroporin highly expressed in the adipose tissue. Its involvement in glycerol metabolism has been widely studied also in humans. Recent
Umberto Laforenza, Manuela F Scaffino, Giulia Gastaldi   +2 more
doaj   +1 more source

Expression and prognostic value of aquaporin 1, 3 in cervical carcinoma in women of Uygur ethnicity from Xinjiang, China. [PDF]

PLoS ONE, 2014
BACKGROUND: Overexpression of several aquaporins has been reported in different types of human cancer but the role of aquaporins in carcinogenesis has not yet been clearly defined.
Rui Chen, Yonghua Shi, Reshalaity Amiduo, Talaf Tuokan, Lalai Suzuk   +4 more
doaj   +1 more source

Vascular Inflammation Is Associated with Loss of Aquaporin 1 Expression on Endothelial Cells and Increased Fluid Leakage in SARS-CoV-2 Infected Golden Syrian Hamsters

Viruses, 2021
Vascular changes represent a characteristic feature of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection leading to a breakdown of the vascular barrier and subsequent edema formation.
Lisa Allnoch, Georg Beythien, Eva Leitzen, Kathrin Becker, Franz-Josef Kaup, Stephanie Stanelle-Bertram, Berfin Schaumburg, Nancy Mounogou Kouassi, Sebastian Beck, Martin Zickler, Vanessa Herder, Gülsah Gabriel, Wolfgang Baumgärtner   +12 more
doaj   +1 more source

High water intake induces primary cilium elongation in renal tubular cells [PDF]

Kidney Research and Clinical Practice
Background The primary cilium protrudes from the cell surface and functions as a mechanosensor. Recently, we found that water intake restriction shortens the primary cilia of renal tubular cells, and a blockage of the shortening disturbs the ability of ...
Min Jung Kong, Sang Jun Han, Sung Young Seu, Ki-Hwan Han, Joshua H. Lipschutz, Kwon Moo Park   +5 more
doaj   +1 more source

The AQP2 mutation V71M causesnephrogenic diabetes insipidus in humans but does not impair the function of a bacterial homolog

FEBS Open Bio, 2015
Several point mutations have been identified in human aquaporins, but their effects on the function of the respective aquaporins are mostly enigmatic. We analyzed the impact of the aquaporin 2 mutation V71M, which causesnephrogenic diabetes insipidus in ...
Noreen Klein, Nadine Kümmerer, Dominika Hobernik, Dirk Schneider   +3 more
doaj   +1 more source

Alleviation of Cerebral Infarction of Rats With Middle Cerebral Artery Occlusion by Inhibition of Aquaporin 4 in the Supraoptic Nucleus

ASN Neuro, 2020
In ischemic stroke, vasopressin hypersecretion is a critical factor of cerebral swelling and brain injury. To clarify neural mechanisms underlying ischemic stroke-evoked vasopressin hypersecretion, we observed the effect of unilateral permanent middle ...
Dan Cui, Shuwei Jia, Jiawei Yu, Dongyang Li, Tong Li, Yang Liu, Jinlong Chang, Xiaoran Wang, Xiaoyu Liu, Yu-Feng Wang   +9 more
doaj   +1 more source