Dehydration reverses vasopressin antagonist-induced diuresis and aquaporin-2 downregulation in rats [PDF]
David Marples +4 more
openalex +1 more source
• Sleep restriction induces clock rhythmic ferroptosis, leading to skin flap necrosis. • MEXOs deliver USP4 to stabilise ARNTL, restoring circadian rhythm and inhibiting ferroptosis. • The METTL3/YTHDF1 m6A axis up‐regulates USP4 in melatonin‐preconditioned BMSCs.
Xiaoqiong Jiang +11 more
wiley +1 more source
Decreased Excretion of Urinary Exosomal Aquaporin-2 in a Puromycin Aminonucleoside-Induced Nephrotic Syndrome Model. [PDF]
Abdeen A +5 more
europepmc +1 more source
Neuronal THY1 Signaling Maintains Astrocytes in a Quiescent State
THY1‐bearing neurons keep astrocytes in a quiescent state via the interaction with ITGB1. Depletion of THY1 supports the development of a partially activated astrocyte phenotype. Neuronal THY1 is involved in the maintenance and restoration of tissue homeostasis in the brain. ABSTRACT THY1 is a cell surface protein of mature neurons.
Juliane Loui +6 more
wiley +1 more source
The Impact of Aquaporin‐4 Deletion on K+‐Induced Astrocytic Swelling Depends on K+ Concentration
Swelling due to 10 mM [K+]o is reduced in astrocytes devoid of aquaporin‐4, while there is no difference between genotypes when exposed to 50 mM [K+]o. The two [K+]o concentrations induce distinct astrocytic Ca2+ signaling in the two genotypes pointing to a possible mechanistic basis of the differences observed. ABSTRACT Astrocytes swell in response to
Cecilie Bugge Bakketun +5 more
wiley +1 more source
A Rare Case of Congenital Nephrogenic Diabetes Insipidus Associated with Aquaporin 2 Gene Mutation and Subsequent Acute Lymphoblastic Leukemia: Impact of Steroids on Kidney Function. [PDF]
Al-Thiabat H +4 more
europepmc +1 more source
Aquaporin-2 expression in the kidney and urine is elevated in rats with monocrotaline-induced pulmonary heart disease. [PDF]
Ouyang S, Chen W, Zeng G, Lei C.
europepmc +1 more source
Changes in aquaporin-2 protein contribute to the urine concentrating defect in rats fed a low-protein diet. [PDF]
Jeff M. Sands +4 more
openalex +1 more source
Mass spectrometry in ocular drug research
Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo +6 more
wiley +1 more source
Sorting Nexin 27 Regulates the Lysosomal Degradation of Aquaporin-2 Protein in the Kidney Collecting Duct. [PDF]
Choi HJ +6 more
europepmc +1 more source

