Results 281 to 290 of about 22,200,369 (327)

Atg7-dependent canonical autophagy regulates the degradation of aquaporin 2 in prolonged hypokalemia. [PDF]

open access: yesSci Rep, 2019
Kim WY   +11 more
europepmc   +1 more source

Investigation of Aquaporin-2 and its mutants with molecular dynamics simulations

open access: gold
Tekin, E. Deniz   +4 more
openalex   +1 more source

Aquaporin-2 is not alone.

Kidney International, 2023
Arginine-vasopressin induces water reabsorption in collecting duct principal cells through the water channels aquaporin (AQP) 2, 3, and 4. Only the presence of these AQPs allows for short-term adjustments of plasma osmolality by arginine-vasopressin. How principal cells maintain the expression of the AQPs is unclear.
E. Klussmann
semanticscholar   +3 more sources

Investigation of the aquaporin‐2 gating mechanism with molecular dynamics simulations

Proteins: Structure, Function, and Bioinformatics, 2021
Aquaporin‐2 plays a vital role in the human kidney as a water passage channel. Any disorder with its function can cause water imbalance and consequently disease in humans, especially nephrogenic diabetes insipidus (NDI).
Hooman Hadidi, R. Kamali, A. Binesh
semanticscholar   +1 more source

Advances in Aquaporin-2 trafficking mechanisms and their implications for treatment of water balance disorders.

American Journal of Physiology - Cell Physiology, 2020
In mammals, conservation of body water is critical for survival and is dependent on the kidneys ability to minimize water loss in the urine during periods of water deprivation.
R. Fenton, S. Murali, H. Moeller
semanticscholar   +1 more source

The vasopressin–aquaporin-2 pathway syndromes

2021
Vasopressin is the key hormone involved in water conservation and regulation of water balance, essential for life. In the renal collecting duct, vasopressin binds to the V2 receptor, increasing water permeability through activation of aquaporin-2 redistribution to the luminal membrane.
Valenti G., Tamma G.
openaire   +3 more sources

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