Results 291 to 300 of about 22,200,369 (327)

Cholemic Nephropathy Causes Acute Kidney Injury and Is Accompanied by Loss of Aquaporin 2 in Collecting Ducts

Hepatology, 2019
Impairment of renal function often occurs in patients with liver disease. Hepatorenal syndrome is a significant cause of acute kidney injury (AKI) in patients with cirrhosis (HRS‐AKI, type 1).
J. H. Bräsen, Young-Seon Mederacke, J. Schmitz, K. Diahovets, Abedalrazag A. Khalifa, B. Hartleben, F. Person, T. Wiech, E. Steenbergen, A. Grosshennig, M. Manns, R. Schmitt, I. Mederacke   +12 more
semanticscholar   +1 more source

Combined Inhibitory Effects of Citrinin, Ochratoxin-A and T-2 Toxin on Aquaporin-2.

Journal of Physical Chemistry B, 2019
Aquaporins form a large family of transmembrane protein channel that facilitates selective and fast water transport across the cell membrane. The inhibition of aquaporin channels leads to many water-related diseases such as nephrogenic diabetes insipidus,
Nikhil Maroli, A. Jayakrishnan, Renuka Ramalingam Manoharan, P. Kolandaivel, K. Krishna   +4 more
semanticscholar   +1 more source

Trimethylamine-N-oxide (TMAO) increased aquaporin-2 expression in spontaneously hypertensive rats

Clinical and experimental hypertension, 2018
Recent evidence suggests that elevated plasma levels of Trimethylamine-N-oxide (TMAO) can prolong the duration of elevated blood pressure in rats. The purpose of this study was to investigate the plasma TMAO level in Spontaneously Hypertensive Rats (SHR)
Min Liu, Q-H Han, Jinglu Yang
semanticscholar   +1 more source

Role of microRNAs in aquaporin 2 regulation

Current Opinion in Nephrology & Hypertension, 2022
Purpose of review The current review aims to present the most recent achievements on the role of microRNAs (miRNAs) on the kidney function to stimulate research in the field and to expand new emerging concepts. Recent findings The focus is on the role of miRNAs in intercellular ...
Petrillo, Federica, Trepiccione, Francesco   +1 more
openaire   +3 more sources

Regulation of Aquaporin-2 Trafficking

2009
Principal cells lining renal collecting ducts control the fine-tuning of body water homeostasis by regulating water reabsorption through the water channels aquaporin-2 (AQP2), aquaporin-3 (AQP3), and aquaporin-4 (AQP4). While the localization of AQP2 is subject to regulation by arginine-vasopressin (AVP), AQP3 and AQP4 are constitutively expressed in ...
NEDVETSKY P. I, BEULSHAUSEN S, ROSENTHAL W, KLUSSMANN E., TAMMA, GRAZIA, VALENTI, Giovanna   +5 more
openaire   +3 more sources

Aquaporin-2 trafficking

2004
Regulation of the water permeability of the apical plasma membrane in collecting duct principal cells is essential for the regulation of renal water excretion, and thus, the regulation of body water balance. The water permeability is partly regulated by trafficking of aquaporin (AQP2) containing vesicles between an intracellular reservoir and the ...
Frische, S., Kwon, T.-H., Frøkiær, Jørgen, Nielsen, Søren   +3 more
openaire   +2 more sources

Aquaporin 2 Mutations in Nephrogenic Diabetes Insipidus

Seminars in Nephrology, 2008
Water reabsorption in the renal collecting duct is regulated by the antidiuretic hormone vasopressin (AVP). When the vasopressin V2 receptor, present on the basolateral site of the renal principal cell, becomes activated by AVP, aquaporin-2 (AQP2) water channels will be inserted in the apical membrane, and in this fashion, water can be reabsorbed from ...
Loonen, A.J.M., Knoers, N.V.A.M., Os, C.H. van, Deen, P.M.T.   +3 more
openaire   +3 more sources

Expression of aquaporin 2 in human endometrium

Fertility and Sterility, 2006
To study the expression of aquaporin-2 (AQP2) in human endometrium.Prospective clinical study.Hospital-based unit for gynecology and obstetrics and research laboratories.Healthy women with proven fertility who were divided into four groups according to LH peak.Endometrial biopsies were obtained from 34 women on cycle days LH+4 to LH+14.Localization of ...
Anna, Hildenbrand, Luther, Lalitkumar, Soren, Nielsen, Kristina, Gemzell-Danielsson, Anneli, Stavreus-Evers   +4 more
openaire   +2 more sources

Regulation of aquaporin-2 by RNA interference

2020
MicroRNAs (miRNAs) are short non-coding RNAs that interact with 3'-untranslated regions of mRNAs. miRNAs modulate gene expression by regulating mRNA translation and provide novel insights into the complex regulation of protein expression and function. In this chapter, we describe the general features of RNA interference, identification of miRNAs, and ...
Hyun Jun, Jung, Eui-Jung, Park, Hyo-Jung, Choi, Tae-Hwan, Kwon   +3 more
openaire   +2 more sources

Repressive regulation of the aquaporin-2 gene

American Journal of Physiology-Renal Physiology, 1996
Expression of aquaporin-2 (AQP2) is exclusively limited to kidney collecting duct cells, and this strictly limited expression could be mediated by transcription of the gene. We first examined AQP2 mRNA expression in many cultured epithelial cells derived from kidney.
M, Furuno, S, Uchida, F, Marumo, S, Sasaki   +3 more
openaire   +2 more sources