Ischemia–Reperfusion Injury: Molecular Mechanisms and Therapeutic Interventions
Multiorgan ischemia–reperfusion injury begins with ischemia‐induced ATP depletion and ionic imbalance, followed by reperfusion‐triggered mitochondrial ROS/RNS bursts, regulated cell death, and DAMP release. Sterile inflammation converges on endothelial–immune–coagulation crosstalk, where NETs drive immunothrombosis, no‐reflow, and remote organ injury ...
Peng An +4 more
wiley +1 more source
Magnetic Resonance Imaging at 14 Tesla of Prostate Biopsies Obtained after Prostatectomy
Fresh prostate biopsies were imaged using a 14 T vertical bore MRI scanner, and the effects of long gradient separation Δ (10–400 ms) were explored. At Δ longer than 10 ms, the percentage of voxels where the Akaike information criteria (AICc) favored a monoexponential model increased, and the apparent diffusion coefficient (ADC) lowered compared to Δ ...
Fredrik Langkilde +4 more
wiley +1 more source
Combustion and Heated Tobacco Cigarettes, but Not E-Cigarettes, Impair Aquaporin-Dependent H<sub>2</sub>O<sub>2</sub> Permeability in ATII-Like Cells. [PDF]
Senise G +3 more
europepmc +1 more source
Summary An uncommon complication following prosthetic laryngoplasty was reported in a 4‐year‐old Andalusian mare. The mare was presented with a previously diagnosed left‐sided recurrent laryngeal neuropathy, after initial evaluation the mare underwent ventriculocordectomy and prosthetic laryngoplasty.
J. L. Sanclemente +2 more
wiley +1 more source
Real-World Multicenter Cohort Study of Inebilizumab vs Low-Dose Rituximab in Neuromyelitis Optica Spectrum Disorders. [PDF]
Xu Q +21 more
europepmc +1 more source
Mechanisms and Clinical Manifestations of Age‐Related Impairment in Wound Healing
ABSTRACT Chronic wounds account for a considerable burden on the overall US healthcare system, affecting an estimated 10.2 million people and costing as much as $148 billion dollars in 2022 alone. Elderly patients suffer disproportionately, as nearly 85% of the chronic wound population is over the age of 65 years old.
Daniel A. Rabin +10 more
wiley +1 more source
Physiological, Genome-Wide Characterization and Expression Analysis of Aquaporin Gene Family of <i>Apocynum venetum</i> in Response to Abiotic Stress. [PDF]
Ma W, Zhang X, Huang Y, Liu Y, Xie W.
europepmc +1 more source
Summary Volatile organic compounds (VOCs) emitted by soil bacteria influence interactions with other soil microbes and plants. While their potential as plant growth promoters is well recognized, their role in promoting plant resilience to abiotic stress and the underlying molecular mechanisms remain poorly understood.
Zulema Carracedo Lorenzo +11 more
wiley +1 more source
Two Aquaporins Mitigate Growth‐Defence Trade‐Offs by Facilitating CO2 and H2O2 Transport in Wheat
ABSTRACT The growth‐defence trade‐offs pose a major challenge to breeding high‐yield and disease‐resistant crops. Aquaporins are membrane channels that facilitate the transport of water and other small compounds, therefore regulating the growth‐defence trade‐offs.
Kai Lu +9 more
wiley +1 more source

