Antipsychotics‐Induced Hyposalivation Mediated by Impaired Salivary Ca2+ Signaling
ABSTRACT Objectives Antipsychotic‐induced salivary dysfunction such as hyposalivation is a prevalent clinical challenge that severely compromises oral health and quality of life. Although typical and atypical antipsychotics have their therapeutic target in the central nervous system, their direct molecular mechanisms within the salivary glands remain ...
Chaelin Chung +4 more
wiley +1 more source
Overexpression of <i>SeTIP2;3</i> and <i>SePIP1;4</i> from <i>Salicornia europaea</i> Enhances Drought Tolerance in <i>Arabidopsis</i>. [PDF]
Zhang R +8 more
europepmc +1 more source
Ion Channel Dysfunction and Therapeutic Targeting in Salivary Gland Disorders
ABSTRACT Objective Salivary gland hypofunction and xerostomia represent major clinical complications of radiation therapy, autoimmune disorders such as Sjögren's disease, and inherited epithelial ion transport defects. This review integrates current knowledge on ion channel dysfunction as a central mechanistic driver of salivary gland pathology and ...
Tarek Mohamed Abd El‐Aziz +6 more
wiley +1 more source
ABSTRACT Drought constitutes a major abiotic stress limiting alfalfa productivity. To elucidate the genetic basis of drought tolerance, a genome‐wide association study (GWAS) was conducted in alfalfa, which identified a CBF/DREB1 family transcription factor designated MsCBF8.
Yangyang Zhang +11 more
wiley +1 more source
Genome-wide analysis of expansin and aquaporin genes and their association with auxin-related metabolites during flower opening in <i>Lonicera macranthoides</i>. [PDF]
Chen Z +8 more
europepmc +1 more source
Deciphering Role of Endophytes in Plant Defences and Biotic Stress Resilience Across Families
ABSTRACT Plant families generate distinct repertoires of specialised metabolites that govern their biotic interactions. Endophytes strengthen host plant defence mechanisms and tolerance to biotic challenges by upregulating metabolite biosynthesis, modifying precursor compounds into more potent forms, or by directly synthesising analogous defence ...
S. Aneeqa Noor +4 more
wiley +1 more source
Control of water excretion in Hydra vulgaris by neural integration. [PDF]
Yamamoto W, Yuste R.
europepmc +1 more source
ABSTRACT Molecular chaperones play a central role in the plant proteostasis machinery by aiding the folding of nascent proteins, preventing aggregation, and repairing or degrading damaged proteins. These functions are especially essential during abiotic and biotic stress, which can destabilise cellular proteins and disrupt metabolic homoeostasis.
Mingfang Yang +10 more
wiley +1 more source
Combustion and Heated Tobacco Cigarettes, but Not E-Cigarettes, Impair Aquaporin-Dependent H<sub>2</sub>O<sub>2</sub> Permeability in ATII-Like Cells. [PDF]
Senise G +3 more
europepmc +1 more source
ABSTRACT Understanding intraspecific variation in drought tolerance is essential for predicting the adaptive capacity of forest species under climate change. Yet, the molecular basis of this variation remains poorly understood in ecologically and economically important conifers.
Muhammad Ahmad +21 more
wiley +1 more source

