Results 221 to 230 of about 39,874 (251)
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Basic Research in Cardiology, 2013
Aquaporins are a group of proteins with high-selective permeability for water. A subgroup called aquaglyceroporins is also permeable to glycerol, urea and a few other solutes. Aquaporin function has mainly been studied in the brain, kidney, glands and skeletal muscle, while the information about aquaporins in the heart is still scarce.
Arkady, Rutkovskiy +2 more
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Aquaporins are a group of proteins with high-selective permeability for water. A subgroup called aquaglyceroporins is also permeable to glycerol, urea and a few other solutes. Aquaporin function has mainly been studied in the brain, kidney, glands and skeletal muscle, while the information about aquaporins in the heart is still scarce.
Arkady, Rutkovskiy +2 more
openaire +2 more sources
2023
Aquaporins (AQP) working as membrane channels facilitated water transport, play vital roles in various physiological progress including cell migration, energy metabolism, inflammation, etc. They are quite important drug targets, but elusive for discovery due to their undruggable properties.
Shuyuan, Wang +2 more
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Aquaporins (AQP) working as membrane channels facilitated water transport, play vital roles in various physiological progress including cell migration, energy metabolism, inflammation, etc. They are quite important drug targets, but elusive for discovery due to their undruggable properties.
Shuyuan, Wang +2 more
openaire +2 more sources
Quarterly Reviews of Biophysics, 2006
1. Introduction 3621.1 The elusive water pores 3621.2 CHIP28 3622. Studies on AQP-1 3632.1 Expression of AQP1 cDNA in Xenopus oocytes 3632.2 Reconstitution of purified AQP1 into artificial lipid bilayers 3642.3 Structural information deduced from the primary sequence 3652.4 Evolution and mammalian AQPs 3653.
Tamir, Gonen, Thomas, Walz
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1. Introduction 3621.1 The elusive water pores 3621.2 CHIP28 3622. Studies on AQP-1 3632.1 Expression of AQP1 cDNA in Xenopus oocytes 3632.2 Reconstitution of purified AQP1 into artificial lipid bilayers 3642.3 Structural information deduced from the primary sequence 3652.4 Evolution and mammalian AQPs 3653.
Tamir, Gonen, Thomas, Walz
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Journal of Membrane Biology, 2004
The prime function of aquaporins (AQPs) is generally believed to be that of increasing water flow rates across membranes by raising their osmotic or hydraulic permeability. In addition, this applies to other small solutes of physiological importance.
A E, Hill +2 more
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The prime function of aquaporins (AQPs) is generally believed to be that of increasing water flow rates across membranes by raising their osmotic or hydraulic permeability. In addition, this applies to other small solutes of physiological importance.
A E, Hill +2 more
openaire +2 more sources
2017
Obesity is one of the most important metabolic disorders of this century and is associated with a cluster of the most dangerous cardiovascular disease risk factors, such as insulin resistance and diabetes , dyslipidemia and hypertension , collectively named Metabolic Syndrome.
Inês V, da Silva, Graça, Soveral
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Obesity is one of the most important metabolic disorders of this century and is associated with a cluster of the most dangerous cardiovascular disease risk factors, such as insulin resistance and diabetes , dyslipidemia and hypertension , collectively named Metabolic Syndrome.
Inês V, da Silva, Graça, Soveral
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2008
The kidneys are the major determinants of body water and electrolyte composition. Thus, comprehending the mechanisms of water transport is essential to understanding mammalian kidney physiology and water balance. Because of its importance to human health, water permeability has been particularly well characterized in the mammalian kidney (Knepper and ...
Kwon, Tae-Hwan +5 more
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The kidneys are the major determinants of body water and electrolyte composition. Thus, comprehending the mechanisms of water transport is essential to understanding mammalian kidney physiology and water balance. Because of its importance to human health, water permeability has been particularly well characterized in the mammalian kidney (Knepper and ...
Kwon, Tae-Hwan +5 more
openaire +3 more sources
2017
The major part of the eye consists of water . Continuous movement of water and ions between the ocular compartments and to the systemic circulation is pivotal for many physiological functions in the eye. The movement of water facilitates removal of the many metabolic products of corneal-, ciliary body-, lens- and retinal metabolism, while maintaining ...
Tran, Thuy Linh +2 more
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The major part of the eye consists of water . Continuous movement of water and ions between the ocular compartments and to the systemic circulation is pivotal for many physiological functions in the eye. The movement of water facilitates removal of the many metabolic products of corneal-, ciliary body-, lens- and retinal metabolism, while maintaining ...
Tran, Thuy Linh +2 more
openaire +3 more sources
Aquaporins: important but elusive drug targets
Nature Reviews Drug Discovery, 2014Alan S Verkman +2 more
exaly
Cytosolic pH regulates root water transport during anoxic stress through gating of aquaporins
Nature, 2003Colette Tournaire-Roux +2 more
exaly