Results 241 to 250 of about 1,287,672 (341)

Changes of Aqueous Humor Cytokine and Chemokine Profiles in Femtosecond Laser-Assisted Cataract Surgery in Comparison to Conventional Phacoemulsification. [PDF]

Ophthalmol Ther
Chychko L, Augustin VA, Son HS, Schickhardt SK, Daniel V, Khoramnia R, Auffarth GU.   +6 more
europepmc   +1 more source

Deep Learning‐Enabled Engineering of a Hyper‐Stable and Soluble MPB70‐83 Antigen for Sensitive Bovine Tuberculosis Surveillance

Microbial Biotechnology, Volume 19, Issue 4, April 2026.
Schematic representation of the research workflow for the efficient diagnosis of bovine tuberculosis employing peptide fusion proteins. ABSTRACT Bovine tuberculosis (bTB) diagnostics are frequently hindered by the structural instability and insolubility of recombinant multi‐epitope proteins in prokaryotic expression systems.
Wen‐Hao Wang, Jia‐Zhen Ge, Ying‐Ying Xie, Guo‐Dong Song, Yijian Liu, Yin‐juan Song, Ren‐ge Li, Rui‐Shuang Li, Zi‐qing Wang, Xin‐Miao Liu, Shuang‐Shuang Guo, Jie Li, Shengli Chen, Na Li, Fuying Zheng, Yuefeng Chu   +15 more
wiley   +1 more source

Effects of Growth and Development on Aqueous Humor Dynamics in Male Dutch Belted Rabbits. [PDF]

Invest Ophthalmol Vis Sci
Gulati V, Fan S, Havens SJ, Rudebush TL, Wenthur SL, Hays CL, Toris CB.   +6 more
europepmc   +1 more source

Senescence‐Driven IL‐17A Inflammatory Circuit Promotes Epithelial–Mesenchymal Transition (EMT) and Progression in Age‐Related Posterior Subcapsular Cataracts

Aging Cell, Volume 25, Issue 4, April 2026.
Using multi‐region human PSC samples, we identified EMT as a consistent pathological feature. Mechanistically, senescent LECs secrete IL‐17A, a representative SASP factor, which activates NF‐κB signaling. NF‐κB further amplifies SASP production, thereby establishing a senescence–inflammation feedback loop that drives EMT, sustains pathological ...
Yan Ni, Yu Ma, Zewen Ren, Yi Zhu, Liangping Liu, Runping Duan, Lu Qin, Yang Chen, Rong Ju, Yingyan Qin, Mingxing Wu   +10 more
wiley   +1 more source

Exploratory Metabolomic Fingerprinting of Aqueous Humor in Healthy Horses and Donkeys, and in Horses with Ocular Pathologies. [PDF]

Animals (Basel)
Corradini I, Jose-Cunilleras E, Nolis P, López-Murcia MM, Mayordomo-Febrer A.   +4 more
europepmc   +1 more source

An Extracellular Matrix Aging Clock Based on Circulating Matrisome Proteins Predicts Biological Aging and Disease

Aging Cell, Volume 25, Issue 4, April 2026.
A 14‐protein extracellular matrix aging clock derived from circulating matrisome proteins predicts chronological and biological age across cohorts and biofluids, distinguishes health from disease, and is modulated by rejuvenation interventions in mice, enabling the nomination of potential ECM targets for drug discovery to promote healthy aging ...
Loet Coenen, Adrian Molière, Benoit Lehallier, Jinte Middeldorp, Collin Y. Ewald   +4 more
wiley   +1 more source

Levels of Zinc, Iron, and Copper in the Aqueous Humor of Patients with Primary Glaucoma. [PDF]

Biomolecules
Li Y, Liu Z, Li Z, Zhu Y, Liang S, Liu H, Xue J, Lin J, Deng Y, Deng C, Zeng S, Zhuo Y, Li Y.   +12 more
europepmc   +1 more source

Circulating angiogenesis‐related biomarkers in sickle cell retinopathy and maculopathy

British Journal of Haematology, Volume 208, Issue 4, Page 1398-1406, April 2026.
Summary Sickle cell disease (SCD), encompassing genotypes such as HbSS and HbSC, leads to retinal complications such as sickle cell retinopathy (SCR) and maculopathy (SCM) through poorly understood mechanisms. This study explored associations of a panel of circulating angiogenesis‐related factors with SCR and SCM.
Rajani P. Brandsen, Ingeborg Klaassen, Renée de Caluwe, Erfan Nur, Bart J. Biemond, Roselie M. H. Diederen, Reinier O. Schlingemann   +6 more
wiley   +1 more source

Lymphatic characteristics of the outflow tract of aqueous humor: An anatomical study in humans. [PDF]

Saudi J Ophthalmol
Kakizaki H, Morishige N, Ishijima K, Konno S, Miki A, Takahashi Y, Lim BXH.   +6 more
europepmc   +1 more source

Protein nanoparticles assemble in plants, display antigenic viral peptides, and produce an epitope‐specific immune response

The FEBS Journal, Volume 293, Issue 7, Page 1891-1907, April 2026.
Current methods to control porcine reproductive and respiratory syndrome, a disease affecting pigs, are insufficient and a safer, more effective vaccine is needed. This study describes the design and plant production of a self‐assembling protein nanoparticle vaccine candidate against this disease.
Jordan T. VanderBurgt, Richard Strasser, Hong Zhu, Angelo Kaldis, Christopher P. Garnham, Rima Menassa   +5 more
wiley   +1 more source