Results 1 to 10 of about 16,541 (253)
Oxidative Damage and Autophagy in the Human Trabecular Meshwork as Related with Ageing [PDF]
PLoS ONE, 2014 Autophagy is an intracellular lysosomal degradation process induced under stress conditions. Autophagy also plays a major role in ocular patho-physiology. Molecular aging does occur in the trabecular meshwork, the main regulator of aqueous humor outflow,
Alessandra Pulliero +2 more
exaly +3 more sources
Schlemm’s Canal and Trabecular Meshwork in Eyes with Primary Open Angle Glaucoma: A Comparative Study Using High-Frequency Ultrasound Biomicroscopy [PDF]
PLoS ONE, 2016 We investigated in vivo changes in Schlemm's canal and the trabecular meshwork in eyes with primary open angle glaucoma (POAG). Relationships between Schlemm's canal diameter, trabecular meshwork thickness, and intraocular pressure (IOP) were examined ...
Xiaoqin Yan, Mu Li, Zhiqi Chen
exaly +3 more sources
Histopathological changes in the trabecular meshwork in primary congenital glaucoma [PDF]
American Journal of Ophthalmology Case ReportsPurpose: To evaluate the morphological changes in the ex-vivo trabecular meshwork TM specimens from patients with primary congenital glaucoma. Methods: Five trabecular meshwork (TM) specimens obtained after microincisional trabeculectomy from 4 patients ...
Aparna Rao
doaj +3 more sources
The TGFβ Induced MicroRNAome of the Trabecular Meshwork [PDF]
CellsPrimary open-angle glaucoma (POAG) is a progressive optic neuropathy with a complex, multifactorial aetiology. Raised intraocular pressure (IOP) is the most important clinically modifiable risk factor for POAG.
Chelsey Doyle +9 more
doaj +6 more sources
PLoS ONE, 2016 Exosomes are emerging as important mediators of cell-matrix interactions by means of specific adhesion proteins. Changes in the tissue-specific exosomal protein expression may underlie pathological conditions whereby extracellular matrix turnover and ...
W Michael Dismuke +2 more
exaly +3 more sources
Sampling trabecular meshwork using TrabEx+ [PDF]
BMC Ophthalmology, 2021 Background To report sampling of the trabecular meshwork using the TrabEx+ (MicroSurgical Technology, Redmond, Washington, USA) device in ab interno trabeculectomy.
Vipul Ramjiani +3 more
doaj +3 more sources
Journal of Functional Biomaterials, 2023 Human trabecular meshwork is a sieve-like tissue with large pores, which plays a vital role in aqueous humor outflow. Dysfunction of this tissue can occur, which leads to glaucoma and permanent vision loss.
Devon J. Crouch +4 more
doaj +2 more sources
Epigenetics of glaucoma in the trabecular meshwork. [PDF]
Clin EpigeneticsGlaucoma represents a predominant cause of irreversible blindness globally, characterized by the association of elevated intraocular pressure (IOP) and retinal ganglion cell loss with dysfunction of the trabecular meshwork (TM), the principal tissue regulating conventional aqueous humor outflow.
Liu Z, Zheng Y, Zhao J.
europepmc +3 more sources
Trabecular meshwork gene expression after selective laser trabeculoplasty.
PLoS ONE, 2011 BackgroundTrabecular meshwork and Schlemm's canal are the tissues appointed to modulate the aqueous humour outflow from the anterior chamber. The impairment of their functions drives to an intraocular pressure increase.
Alberto Izzotti +4 more
doaj +2 more sources
Exploiting biomaterial approaches to manufacture an artificial trabecular meshwork: A progress report [PDF]
Biomaterials and Biosystems, 2021 Glaucoma is the second leading cause of irreversible blindness worldwide. Glaucoma is a progressive optic neuropathy in which permanent loss of peripheral vision results from neurodegeneration in the optic nerve head.
Devon J. Crouch +4 more
doaj +2 more sources