Results 1 to 10 of about 14,535 (168)
Schlemm’s Canal and Trabecular Meshwork in Eyes with Primary Open Angle Glaucoma: A Comparative Study Using High-Frequency Ultrasound Biomicroscopy [PDF]
PLoS ONE, 2016 We investigated in vivo changes in Schlemm's canal and the trabecular meshwork in eyes with primary open angle glaucoma (POAG). Relationships between Schlemm's canal diameter, trabecular meshwork thickness, and intraocular pressure (IOP) were examined ...
Yinwei Song, Xiaoqin Yan, Mu Li
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Oxidative Damage and Autophagy in the Human Trabecular Meshwork as Related with Ageing
PLoS ONE, 2014 Autophagy is an intracellular lysosomal degradation process induced under stress conditions. Autophagy also plays a major role in ocular patho-physiology. Molecular aging does occur in the trabecular meshwork, the main regulator of aqueous humor outflow,
Alessandra Pulliero +2 more
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PLoS ONE, 2016 Exosomes are emerging as important mediators of cell-matrix interactions by means of specific adhesion proteins. Changes in the tissue-specific exosomal protein expression may underlie pathological conditions whereby extracellular matrix turnover and ...
W Daniel Stamer +2 more
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Transcriptomic Differences Between Human Trabecular Meshwork Stem Cells and Trabecular Meshwork Cells Reveal Specific Biomarker Profiles [PDF]
Current Issues in Molecular BiologyGlaucoma is a leading cause of irreversible blindness, normally associated with dysfunction and degeneration of the trabecular meshwork (TM) as the primary cause.
Rong Du +5 more
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Journal of Functional Biomaterials, 2023 Human trabecular meshwork is a sieve-like tissue with large pores, which plays a vital role in aqueous humor outflow. Dysfunction of this tissue can occur, which leads to glaucoma and permanent vision loss.
Devon J. Crouch +4 more
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PLoS ONE, 2021 Trabecular meshwork constitutes the conventional outflow pathway and controls intraocular pressure by regulating aqueous outflow. Mechanical stimulation has been studied as one of the triggers to regulate aqueous outflow in trabecular meshwork, but it is
Takatoshi Uchida +7 more
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Mesenchymal stem cell-derived exosomes protect trabecular meshwork from oxidative stress
Scientific Reports, 2021 This study aims to investigate the beneficial effects of exosomes derived from bone marrow mesenchymal stem cells (BMSCs) on trabecular meshwork cells under oxidative stress and predict candidate genes associated with this process.
Ying-chao Li +5 more
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Sampling trabecular meshwork using TrabEx+
BMC Ophthalmology, 2021 Background To report sampling of the trabecular meshwork using the TrabEx+ (MicroSurgical Technology, Redmond, Washington, USA) device in ab interno trabeculectomy.
Vipul Ramjiani +3 more
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Pharmaceutics, 2021 In glaucoma therapy, nanoparticles (NPs) are a favorable tool for delivering drugs to the outflow tissues of the anterior chamber of the eye where disease development and progression take place.
Tobias Sonntag +5 more
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Tetramethylpyrazine (TMP), an Active Ingredient of Chinese Herb Medicine Chuanxiong, Attenuates the Degeneration of Trabecular Meshwork through SDF-1/CXCR4 Axis. [PDF]
PLoS ONE, 2015 A traditional Chinese medicine, Tetramethylpyrazine (TMP), has been prescribed as a complementary treatment for glaucoma to improve patient prognosis. However, the pharmacological mechanism of action of TMP is poorly understood.
Na Yu +12 more
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