Results 11 to 20 of about 16,541 (253)
The trabecular meshwork in acute and chronic angle closure glaucoma.
Indian Journal of Ophthalmology, 2001 PURPOSE: To determine the effect of acute and chronic primary angle closure glaucoma (PACG) on the trabecular meshwork. METHODS: Trabecular specimens of 16 consecutive patients with primary angle closure glaucoma (PACG)--6 acute PACG eyes, and 10 chronic
Sihota R +5 more
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Characterizing the expression profile of Dexras1 in human trabecular meshwork cells [PDF]
Biochemistry and Biophysics ReportsCorticosteroids are a mainstay therapy for the treatment of ocular and systemic inflammatory conditions but are associated with a significant risk of intraocular pressure elevation, or ocular hypertension.
ChihWei Chen +4 more
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Transcriptomic Differences Between Human Trabecular Meshwork Stem Cells and Trabecular Meshwork Cells Reveal Specific Biomarker Profiles [PDF]
Current Issues in Molecular BiologyGlaucoma is a leading cause of irreversible blindness, normally associated with dysfunction and degeneration of the trabecular meshwork (TM) as the primary cause.
Rong Du +5 more
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PLoS ONE, 2021 Trabecular meshwork constitutes the conventional outflow pathway and controls intraocular pressure by regulating aqueous outflow. Mechanical stimulation has been studied as one of the triggers to regulate aqueous outflow in trabecular meshwork, but it is
Takatoshi Uchida +7 more
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Dexamethasone Stiffens Trabecular Meshwork, Trabecular Meshwork Cells, and Matrix [PDF]
Investigative Opthalmology & Visual Science, 2015 Treatment with corticosteroids can result in ocular hypertension and may lead to the development of steroid-induced glaucoma. The extent to which biomechanical changes in trabecular meshwork (TM) cells and extracellular matrix (ECM) contribute toward this dysfunction is poorly understood.Primary human TM (HTM) cells were cultured for either 3 days or 4
Vijay Krishna, Raghunathan +6 more
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Mesenchymal stem cell-derived exosomes protect trabecular meshwork from oxidative stress
Scientific Reports, 2021 This study aims to investigate the beneficial effects of exosomes derived from bone marrow mesenchymal stem cells (BMSCs) on trabecular meshwork cells under oxidative stress and predict candidate genes associated with this process.
Ying-chao Li +5 more
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Clinical Ophthalmology, 2017 Bernd Junker,1 Jens F Jordan,2 Carsten Framme,1 Amelie Pielen1 1University Eye Hospital, Medical School Hannover, Hannover, 2Eye Center, Medical Center, University of Freiburg, Freiburg, Germany Importance: This study is the first description of the ...
Junker B, Jordan JF, Framme C, Pielen A
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Apoptosis in the trabecular meshwork of glaucomatous patients.
Molecular vision, 2008 Peer ...
Baleriola, Jimena +5 more
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Trabecular meshwork stiffness in glaucoma [PDF]
Experimental Eye Research, 2017 Alterations in stiffness of the trabecular meshwork (TM) may play an important role in primary open-angle glaucoma (POAG), the second leading cause of blindness. Specifically, certain data suggest an association between elevated intraocular pressure (IOP) and increased TM stiffness; however, the underlying link between TM stiffness and IOP remains ...
Ke, Wang +3 more
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Pharmaceutics, 2021 In glaucoma therapy, nanoparticles (NPs) are a favorable tool for delivering drugs to the outflow tissues of the anterior chamber of the eye where disease development and progression take place.
Tobias Sonntag +5 more
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